Mycobacterial dynamin-like protein IniA mediates membrane fission

Tuberculosis drugs induce the expression of IniA, but so far little has been known about its structure and function. Here the authors present the apo and GTP bound crystal structures of Mycobacterium smegmatis IniA, which folds as a bacterial dynamin-like protein and show that IniA mediates membrane...

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Auteurs principaux: Manfu Wang, Xiangyang Guo, Xiuna Yang, Bing Zhang, Jie Ren, Aijun Liu, Yajun Ran, Bing Yan, Fang Chen, Luke W. Guddat, Junjie Hu, Jun Li, Zihe Rao
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/a1dcbbca4dc249008861d887755f12f9
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