Lipid droplet and peroxisome biogenesis occur at the same ER subdomains

Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.

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Autores principales: Amit S. Joshi, Benjamin Nebenfuehr, Vineet Choudhary, Prasanna Satpute-Krishnan, Tim P. Levine, Andy Golden, William A. Prinz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc71
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spelling oai:doaj.org-article:a1e2c94e0d0c4f8b9fcf9587d37bfc712021-12-02T16:49:18ZLipid droplet and peroxisome biogenesis occur at the same ER subdomains10.1038/s41467-018-05277-32041-1723https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc712018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05277-3https://doaj.org/toc/2041-1723Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.Amit S. JoshiBenjamin NebenfuehrVineet ChoudharyPrasanna Satpute-KrishnanTim P. LevineAndy GoldenWilliam A. PrinzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amit S. Joshi
Benjamin Nebenfuehr
Vineet Choudhary
Prasanna Satpute-Krishnan
Tim P. Levine
Andy Golden
William A. Prinz
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
description Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.
format article
author Amit S. Joshi
Benjamin Nebenfuehr
Vineet Choudhary
Prasanna Satpute-Krishnan
Tim P. Levine
Andy Golden
William A. Prinz
author_facet Amit S. Joshi
Benjamin Nebenfuehr
Vineet Choudhary
Prasanna Satpute-Krishnan
Tim P. Levine
Andy Golden
William A. Prinz
author_sort Amit S. Joshi
title Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_short Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_full Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_fullStr Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_full_unstemmed Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_sort lipid droplet and peroxisome biogenesis occur at the same er subdomains
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc71
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