Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.
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2018
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oai:doaj.org-article:a1e2c94e0d0c4f8b9fcf9587d37bfc712021-12-02T16:49:18ZLipid droplet and peroxisome biogenesis occur at the same ER subdomains10.1038/s41467-018-05277-32041-1723https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc712018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05277-3https://doaj.org/toc/2041-1723Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.Amit S. JoshiBenjamin NebenfuehrVineet ChoudharyPrasanna Satpute-KrishnanTim P. LevineAndy GoldenWilliam A. PrinzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Amit S. Joshi Benjamin Nebenfuehr Vineet Choudhary Prasanna Satpute-Krishnan Tim P. Levine Andy Golden William A. Prinz Lipid droplet and peroxisome biogenesis occur at the same ER subdomains |
description |
Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog. |
format |
article |
author |
Amit S. Joshi Benjamin Nebenfuehr Vineet Choudhary Prasanna Satpute-Krishnan Tim P. Levine Andy Golden William A. Prinz |
author_facet |
Amit S. Joshi Benjamin Nebenfuehr Vineet Choudhary Prasanna Satpute-Krishnan Tim P. Levine Andy Golden William A. Prinz |
author_sort |
Amit S. Joshi |
title |
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains |
title_short |
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains |
title_full |
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains |
title_fullStr |
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains |
title_full_unstemmed |
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains |
title_sort |
lipid droplet and peroxisome biogenesis occur at the same er subdomains |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc71 |
work_keys_str_mv |
AT amitsjoshi lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains AT benjaminnebenfuehr lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains AT vineetchoudhary lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains AT prasannasatputekrishnan lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains AT timplevine lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains AT andygolden lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains AT williamaprinz lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains |
_version_ |
1718383352125325312 |