Lipid droplet and peroxisome biogenesis occur at the same ER subdomains

Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.

Saved in:
Bibliographic Details
Main Authors: Amit S. Joshi, Benjamin Nebenfuehr, Vineet Choudhary, Prasanna Satpute-Krishnan, Tim P. Levine, Andy Golden, William A. Prinz
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc71
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:doaj.org-article:a1e2c94e0d0c4f8b9fcf9587d37bfc71
record_format dspace
spelling oai:doaj.org-article:a1e2c94e0d0c4f8b9fcf9587d37bfc712021-12-02T16:49:18ZLipid droplet and peroxisome biogenesis occur at the same ER subdomains10.1038/s41467-018-05277-32041-1723https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc712018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05277-3https://doaj.org/toc/2041-1723Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.Amit S. JoshiBenjamin NebenfuehrVineet ChoudharyPrasanna Satpute-KrishnanTim P. LevineAndy GoldenWilliam A. PrinzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amit S. Joshi
Benjamin Nebenfuehr
Vineet Choudhary
Prasanna Satpute-Krishnan
Tim P. Levine
Andy Golden
William A. Prinz
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
description Lipid droplets (LDs) and peroxisomes are both generated by budding off the endoplasmic reticulum (ER). Here, the authors show that the yeast protein Pex30 marks ER subdomains where both LD and peroxisome biogenesis occurs, and identify MCTP2 as the putative mammalian Pex30 ortholog.
format article
author Amit S. Joshi
Benjamin Nebenfuehr
Vineet Choudhary
Prasanna Satpute-Krishnan
Tim P. Levine
Andy Golden
William A. Prinz
author_facet Amit S. Joshi
Benjamin Nebenfuehr
Vineet Choudhary
Prasanna Satpute-Krishnan
Tim P. Levine
Andy Golden
William A. Prinz
author_sort Amit S. Joshi
title Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_short Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_full Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_fullStr Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_full_unstemmed Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
title_sort lipid droplet and peroxisome biogenesis occur at the same er subdomains
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/a1e2c94e0d0c4f8b9fcf9587d37bfc71
work_keys_str_mv AT amitsjoshi lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains
AT benjaminnebenfuehr lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains
AT vineetchoudhary lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains
AT prasannasatputekrishnan lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains
AT timplevine lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains
AT andygolden lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains
AT williamaprinz lipiddropletandperoxisomebiogenesisoccuratthesameersubdomains
_version_ 1718383352125325312