Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1

PU.1 is a master TF of hematopoietic lineage differentiation. Here the authors analyse properties of PU.1 DNA-binding in vitro and genome-wide in vivo across different cell types with native or ectopic PU.1 expression, and uncover the mechanisms governing the pioneering and redistribution capabiliti...

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Autores principales:	Julia Minderjahn, Andreas Schmidt, Andreas Fuchs, Rudolf Schill, Johanna Raithel, Magda Babina, Christian Schmidl, Claudia Gebhard, Sandra Schmidhofer, Karina Mendes, Anna Ratermann, Dagmar Glatz, Margit Nützel, Matthias Edinger, Petra Hoffmann, Rainer Spang, Gernot Längst, Axel Imhof, Michael Rehli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a1e8607ec20a48c6b05e13fafbd8d67e
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spelling	oai:doaj.org-article:a1e8607ec20a48c6b05e13fafbd8d67e2021-12-02T14:41:03ZMechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.110.1038/s41467-019-13960-22041-1723https://doaj.org/article/a1e8607ec20a48c6b05e13fafbd8d67e2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13960-2https://doaj.org/toc/2041-1723PU.1 is a master TF of hematopoietic lineage differentiation. Here the authors analyse properties of PU.1 DNA-binding in vitro and genome-wide in vivo across different cell types with native or ectopic PU.1 expression, and uncover the mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1.Julia MinderjahnAndreas SchmidtAndreas FuchsRudolf SchillJohanna RaithelMagda BabinaChristian SchmidlClaudia GebhardSandra SchmidhoferKarina MendesAnna RatermannDagmar GlatzMargit NützelMatthias EdingerPetra HoffmannRainer SpangGernot LängstAxel ImhofMichael RehliNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julia Minderjahn Andreas Schmidt Andreas Fuchs Rudolf Schill Johanna Raithel Magda Babina Christian Schmidl Claudia Gebhard Sandra Schmidhofer Karina Mendes Anna Ratermann Dagmar Glatz Margit Nützel Matthias Edinger Petra Hoffmann Rainer Spang Gernot Längst Axel Imhof Michael Rehli Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
description	PU.1 is a master TF of hematopoietic lineage differentiation. Here the authors analyse properties of PU.1 DNA-binding in vitro and genome-wide in vivo across different cell types with native or ectopic PU.1 expression, and uncover the mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1.
format	article
author	Julia Minderjahn Andreas Schmidt Andreas Fuchs Rudolf Schill Johanna Raithel Magda Babina Christian Schmidl Claudia Gebhard Sandra Schmidhofer Karina Mendes Anna Ratermann Dagmar Glatz Margit Nützel Matthias Edinger Petra Hoffmann Rainer Spang Gernot Längst Axel Imhof Michael Rehli
author_facet	Julia Minderjahn Andreas Schmidt Andreas Fuchs Rudolf Schill Johanna Raithel Magda Babina Christian Schmidl Claudia Gebhard Sandra Schmidhofer Karina Mendes Anna Ratermann Dagmar Glatz Margit Nützel Matthias Edinger Petra Hoffmann Rainer Spang Gernot Längst Axel Imhof Michael Rehli
author_sort	Julia Minderjahn
title	Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
title_short	Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
title_full	Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
title_fullStr	Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
title_full_unstemmed	Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
title_sort	mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer pu.1
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a1e8607ec20a48c6b05e13fafbd8d67e
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Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1

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