Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304

The data presented here are related to the article entitled “New contributions to the drug profile of TNFα inhibitor SPD304: affinity, selectivity ADMET considerations” published in the European Journal of pharmacology. As DMSO is usually used as a co-solvent to dissolve low aqueous soluble small mo...

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Autores principales:	Ghada Attia, Aïda Mascret, Chouki Zerrouki, Najla Fourati, Maité Sylla-Iyarreta Veitía, Marc Port
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	SPD304 Surface acoustic wave biosensor TNFα Affinity DMSO cosolvent Computer applications to medicine. Medical informatics R858-859.7 Science (General) Q1-390
Acceso en línea:	https://doaj.org/article/a1f0f64413a3496cb3c7d4937f2efd8d
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spelling	oai:doaj.org-article:a1f0f64413a3496cb3c7d4937f2efd8d2021-11-26T04:31:29ZData of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD3042352-340910.1016/j.dib.2021.107610https://doaj.org/article/a1f0f64413a3496cb3c7d4937f2efd8d2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2352340921008854https://doaj.org/toc/2352-3409The data presented here are related to the article entitled “New contributions to the drug profile of TNFα inhibitor SPD304: affinity, selectivity ADMET considerations” published in the European Journal of pharmacology. As DMSO is usually used as a co-solvent to dissolve low aqueous soluble small molecules, such as SPD304, we have investigated the influence of its concentration on the kinetic of interaction between tumor necrosis factor α (TNF-α) and its inhibitor, SPD304. The presented data, acquired using a surface acoustic wave sensor, can be used in further biological studies to compare the kinetic of interaction between proteins/small molecules in general and TNFα/inhibitors in particular. The estimated dissociation constant can be compared to other ones to statute on the degree of affinity between a protein and a given molecule.Ghada AttiaAïda MascretChouki ZerroukiNajla FouratiMaité Sylla-Iyarreta VeitíaMarc PortElsevierarticleSPD304Surface acoustic wave biosensorTNFαAffinityDMSO cosolventComputer applications to medicine. Medical informaticsR858-859.7Science (General)Q1-390ENData in Brief, Vol 39, Iss , Pp 107610- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	SPD304 Surface acoustic wave biosensor TNFα Affinity DMSO cosolvent Computer applications to medicine. Medical informatics R858-859.7 Science (General) Q1-390
spellingShingle	SPD304 Surface acoustic wave biosensor TNFα Affinity DMSO cosolvent Computer applications to medicine. Medical informatics R858-859.7 Science (General) Q1-390 Ghada Attia Aïda Mascret Chouki Zerrouki Najla Fourati Maité Sylla-Iyarreta Veitía Marc Port Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304
description	The data presented here are related to the article entitled “New contributions to the drug profile of TNFα inhibitor SPD304: affinity, selectivity ADMET considerations” published in the European Journal of pharmacology. As DMSO is usually used as a co-solvent to dissolve low aqueous soluble small molecules, such as SPD304, we have investigated the influence of its concentration on the kinetic of interaction between tumor necrosis factor α (TNF-α) and its inhibitor, SPD304. The presented data, acquired using a surface acoustic wave sensor, can be used in further biological studies to compare the kinetic of interaction between proteins/small molecules in general and TNFα/inhibitors in particular. The estimated dissociation constant can be compared to other ones to statute on the degree of affinity between a protein and a given molecule.
format	article
author	Ghada Attia Aïda Mascret Chouki Zerrouki Najla Fourati Maité Sylla-Iyarreta Veitía Marc Port
author_facet	Ghada Attia Aïda Mascret Chouki Zerrouki Najla Fourati Maité Sylla-Iyarreta Veitía Marc Port
author_sort	Ghada Attia
title	Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304
title_short	Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304
title_full	Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304
title_fullStr	Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304
title_full_unstemmed	Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304
title_sort	data of the quantification of the influence of dmso concentration on the kinetic of interaction between tnfα and spd304
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/a1f0f64413a3496cb3c7d4937f2efd8d
work_keys_str_mv	AT ghadaattia dataofthequantificationoftheinfluenceofdmsoconcentrationonthekineticofinteractionbetweentnfaandspd304 AT aidamascret dataofthequantificationoftheinfluenceofdmsoconcentrationonthekineticofinteractionbetweentnfaandspd304 AT choukizerrouki dataofthequantificationoftheinfluenceofdmsoconcentrationonthekineticofinteractionbetweentnfaandspd304 AT najlafourati dataofthequantificationoftheinfluenceofdmsoconcentrationonthekineticofinteractionbetweentnfaandspd304 AT maitesyllaiyarretaveitia dataofthequantificationoftheinfluenceofdmsoconcentrationonthekineticofinteractionbetweentnfaandspd304 AT marcport dataofthequantificationoftheinfluenceofdmsoconcentrationonthekineticofinteractionbetweentnfaandspd304
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Data of the quantification of the influence of DMSO concentration on the kinetic of interaction between TNFα and SPD304

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