Further Understanding about the Mechanism of Vitamin D on Blood Pressure

Globally, the prevalence of vitamin D deficiency and hypertension is both increasing. Various studies have also identified that both are likely to have causality relationships. The mechanisms and possibilities of such relationships will be discussed in this article. This literature study takes syste...

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Autores principales:	Farapti Farapti, Chusnul Fadilla
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Gadjah Mada 2021
Materias:	vitamin d, blood pressure, hypertension Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/a1f51e50994b4139b1c8bb7253eab1a6
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spelling	oai:doaj.org-article:a1f51e50994b4139b1c8bb7253eab1a62021-11-15T06:08:46ZFurther Understanding about the Mechanism of Vitamin D on Blood Pressure2338-94272338-948610.22146/ijp.1439https://doaj.org/article/a1f51e50994b4139b1c8bb7253eab1a62021-09-01T00:00:00Zhttps://jurnal.ugm.ac.id/v3/IJP/article/view/1439https://doaj.org/toc/2338-9427https://doaj.org/toc/2338-9486Globally, the prevalence of vitamin D deficiency and hypertension is both increasing. Various studies have also identified that both are likely to have causality relationships. The mechanisms and possibilities of such relationships will be discussed in this article. This literature study takes systematic review and meta-analysis research as well as randomly other research to complete the discussion on the role, effects, and mechanisms of vitamin D to blood pressure. Vitamin D is a fat-soluble vitamin that can be produced by the body and the most proper measurement using 25(OH)D. Low vitamin D is one of the risk factors for increased blood pressure (BP). Administration of vitamin D seems beneficial to lowering BP through various mechanisms including inhibit renin gene expression, maintain PTH levels and calcium homeostasis, vasodilatation BP, and decrease sympathetic nerve activity. Research with vitamin D supplementation reported random data between effective and whether or not to decrease BP. Vitamin D can be significantly beneficial in only some conditions although overall it has increased levels of 25(OH)D. However, although vitamin D is very good for health improvement, the use of vitamin D specifically as an antihypertensive still needs more understanding and research on the conditions that have proven effective in their use.Farapti FaraptiChusnul FadillaUniversitas Gadjah Madaarticlevitamin d, blood pressure, hypertensionPharmacy and materia medicaRS1-441ENIndonesian Journal of Pharmacy, Pp 314-327 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	vitamin d, blood pressure, hypertension Pharmacy and materia medica RS1-441
spellingShingle	vitamin d, blood pressure, hypertension Pharmacy and materia medica RS1-441 Farapti Farapti Chusnul Fadilla Further Understanding about the Mechanism of Vitamin D on Blood Pressure
description	Globally, the prevalence of vitamin D deficiency and hypertension is both increasing. Various studies have also identified that both are likely to have causality relationships. The mechanisms and possibilities of such relationships will be discussed in this article. This literature study takes systematic review and meta-analysis research as well as randomly other research to complete the discussion on the role, effects, and mechanisms of vitamin D to blood pressure. Vitamin D is a fat-soluble vitamin that can be produced by the body and the most proper measurement using 25(OH)D. Low vitamin D is one of the risk factors for increased blood pressure (BP). Administration of vitamin D seems beneficial to lowering BP through various mechanisms including inhibit renin gene expression, maintain PTH levels and calcium homeostasis, vasodilatation BP, and decrease sympathetic nerve activity. Research with vitamin D supplementation reported random data between effective and whether or not to decrease BP. Vitamin D can be significantly beneficial in only some conditions although overall it has increased levels of 25(OH)D. However, although vitamin D is very good for health improvement, the use of vitamin D specifically as an antihypertensive still needs more understanding and research on the conditions that have proven effective in their use.
format	article
author	Farapti Farapti Chusnul Fadilla
author_facet	Farapti Farapti Chusnul Fadilla
author_sort	Farapti Farapti
title	Further Understanding about the Mechanism of Vitamin D on Blood Pressure
title_short	Further Understanding about the Mechanism of Vitamin D on Blood Pressure
title_full	Further Understanding about the Mechanism of Vitamin D on Blood Pressure
title_fullStr	Further Understanding about the Mechanism of Vitamin D on Blood Pressure
title_full_unstemmed	Further Understanding about the Mechanism of Vitamin D on Blood Pressure
title_sort	further understanding about the mechanism of vitamin d on blood pressure
publisher	Universitas Gadjah Mada
publishDate	2021
url	https://doaj.org/article/a1f51e50994b4139b1c8bb7253eab1a6
work_keys_str_mv	AT faraptifarapti furtherunderstandingaboutthemechanismofvitamindonbloodpressure AT chusnulfadilla furtherunderstandingaboutthemechanismofvitamindonbloodpressure
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Further Understanding about the Mechanism of Vitamin D on Blood Pressure

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