The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis

The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis

Mediator is a multiprotein complex required to activate gene transcription by RNAPII. Here, the authors report that MED12 and MED13 are conditional positive regulators that facilitate the expression of genes depleted in active chromatin marks and the induction of gene expression in response to envir...

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Autores principales: Qikun Liu, Sylvain Bischof, C. Jake Harris, Zhenhui Zhong, Lingyu Zhan, Calvin Nguyen, Andrew Rashoff, William D. Barshop, Fei Sun, Suhua Feng, Magdalena Potok, Javier Gallego-Bartolome, Jixian Zhai, James A. Wohlschlegel, Michael F. Carey, Jeffrey A. Long, Steven E. Jacobsen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a1f7481a95074346be1780a4740809f3
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spelling oai:doaj.org-article:a1f7481a95074346be1780a4740809f32021-12-02T15:57:09ZThe characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis10.1038/s41467-020-16651-52041-1723https://doaj.org/article/a1f7481a95074346be1780a4740809f32020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16651-5https://doaj.org/toc/2041-1723Mediator is a multiprotein complex required to activate gene transcription by RNAPII. Here, the authors report that MED12 and MED13 are conditional positive regulators that facilitate the expression of genes depleted in active chromatin marks and the induction of gene expression in response to environmental stimuli in Arabidopsis.Qikun LiuSylvain BischofC. Jake HarrisZhenhui ZhongLingyu ZhanCalvin NguyenAndrew RashoffWilliam D. BarshopFei SunSuhua FengMagdalena PotokJavier Gallego-BartolomeJixian ZhaiJames A. WohlschlegelMichael F. CareyJeffrey A. LongSteven E. JacobsenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qikun Liu
Sylvain Bischof
C. Jake Harris
Zhenhui Zhong
Lingyu Zhan
Calvin Nguyen
Andrew Rashoff
William D. Barshop
Fei Sun
Suhua Feng
Magdalena Potok
Javier Gallego-Bartolome
Jixian Zhai
James A. Wohlschlegel
Michael F. Carey
Jeffrey A. Long
Steven E. Jacobsen
The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
description Mediator is a multiprotein complex required to activate gene transcription by RNAPII. Here, the authors report that MED12 and MED13 are conditional positive regulators that facilitate the expression of genes depleted in active chromatin marks and the induction of gene expression in response to environmental stimuli in Arabidopsis.
format article
author Qikun Liu
Sylvain Bischof
C. Jake Harris
Zhenhui Zhong
Lingyu Zhan
Calvin Nguyen
Andrew Rashoff
William D. Barshop
Fei Sun
Suhua Feng
Magdalena Potok
Javier Gallego-Bartolome
Jixian Zhai
James A. Wohlschlegel
Michael F. Carey
Jeffrey A. Long
Steven E. Jacobsen
author_facet Qikun Liu
Sylvain Bischof
C. Jake Harris
Zhenhui Zhong
Lingyu Zhan
Calvin Nguyen
Andrew Rashoff
William D. Barshop
Fei Sun
Suhua Feng
Magdalena Potok
Javier Gallego-Bartolome
Jixian Zhai
James A. Wohlschlegel
Michael F. Carey
Jeffrey A. Long
Steven E. Jacobsen
author_sort Qikun Liu
title The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
title_short The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
title_full The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
title_fullStr The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
title_full_unstemmed The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
title_sort characterization of mediator 12 and 13 as conditional positive gene regulators in arabidopsis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a1f7481a95074346be1780a4740809f3
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