Quantification of purified endogenous miRNAs with high sensitivity and specificity

MicroRNAs are potentially powerful biomarkers, though clinical use requires rapid and reliable profiling. Here the authors report amplification-free multicolour single-molecule imaging with single base mismatch sensitivity.

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Auteurs principaux:	Soochul Shin, Yoonseok Jung, Heesoo Uhm, Minseok Song, Soomin Son, Jiyoung Goo, Cherlhyun Jeong, Ji-Joon Song, V. Narry Kim, Sungchul Hohng
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/a1f97de236b54183ad3bf6dbebd4a004
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spelling	oai:doaj.org-article:a1f97de236b54183ad3bf6dbebd4a0042021-12-02T16:56:35ZQuantification of purified endogenous miRNAs with high sensitivity and specificity10.1038/s41467-020-19865-92041-1723https://doaj.org/article/a1f97de236b54183ad3bf6dbebd4a0042020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19865-9https://doaj.org/toc/2041-1723MicroRNAs are potentially powerful biomarkers, though clinical use requires rapid and reliable profiling. Here the authors report amplification-free multicolour single-molecule imaging with single base mismatch sensitivity.Soochul ShinYoonseok JungHeesoo UhmMinseok SongSoomin SonJiyoung GooCherlhyun JeongJi-Joon SongV. Narry KimSungchul HohngNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Soochul Shin Yoonseok Jung Heesoo Uhm Minseok Song Soomin Son Jiyoung Goo Cherlhyun Jeong Ji-Joon Song V. Narry Kim Sungchul Hohng Quantification of purified endogenous miRNAs with high sensitivity and specificity
description	MicroRNAs are potentially powerful biomarkers, though clinical use requires rapid and reliable profiling. Here the authors report amplification-free multicolour single-molecule imaging with single base mismatch sensitivity.
format	article
author	Soochul Shin Yoonseok Jung Heesoo Uhm Minseok Song Soomin Son Jiyoung Goo Cherlhyun Jeong Ji-Joon Song V. Narry Kim Sungchul Hohng
author_facet	Soochul Shin Yoonseok Jung Heesoo Uhm Minseok Song Soomin Son Jiyoung Goo Cherlhyun Jeong Ji-Joon Song V. Narry Kim Sungchul Hohng
author_sort	Soochul Shin
title	Quantification of purified endogenous miRNAs with high sensitivity and specificity
title_short	Quantification of purified endogenous miRNAs with high sensitivity and specificity
title_full	Quantification of purified endogenous miRNAs with high sensitivity and specificity
title_fullStr	Quantification of purified endogenous miRNAs with high sensitivity and specificity
title_full_unstemmed	Quantification of purified endogenous miRNAs with high sensitivity and specificity
title_sort	quantification of purified endogenous mirnas with high sensitivity and specificity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a1f97de236b54183ad3bf6dbebd4a004
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_version_	1718382816701448192

Quantification of purified endogenous miRNAs with high sensitivity and specificity

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