T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy.

T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy.

HIV cerebrospinal fluid (CSF) escape, where HIV is suppressed in blood but detectable in CSF, occurs when HIV persists in the CNS despite antiretroviral therapy (ART). To determine the virus producing cell type and whether lowered CSF ART levels are responsible for CSF escape, we collected blood and...

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Autores principales: Gila Lustig, Sandile Cele, Farina Karim, Anne Derache, Abigail Ngoepe, Khadija Khan, Bernadett I Gosnell, Mahomed-Yunus S Moosa, Ntombi Ntshuba, Suzaan Marais, Prakash M Jeena, Katya Govender, John Adamson, Henrik Kløverpris, Ravindra K Gupta, Rohen Harrichandparsad, Vinod B Patel, Alex Sigal
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/a1fcfa49647c48ec8249fe5457393dfd
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