CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status.

CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status.

CD44 marks stem cell-like cells in a number of tumour types, including colorectal cancer (CRC), while aberrant CD44 expression conveys increased tumourigenic, invasive, and metastatic potential. Previous data indicate that CD44 is a direct target of p53-mediated transcriptional repression in breast...

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Autores principales: Jurrit Zeilstra, Sander P J Joosten, Louis Vermeulen, Jan Koster, Jan Paul Medema, Rogier Versteeg, Marcel Spaargaren, Steven T Pals
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Medicine
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Science
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Acceso en línea:https://doaj.org/article/a2015b6f06404d929df298986c786d52
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