The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity

The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity

Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposing functions in regulating the anti-tumour immune r...

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Autores principales: Damya Laoui, Jiri Keirsse, Yannick Morias, Eva Van Overmeire, Xenia Geeraerts, Yvon Elkrim, Mate Kiss, Evangelia Bolli, Qods Lahmar, Dorine Sichien, Jens Serneels, Charlotte L. Scott, Louis Boon, Patrick De Baetselier, Massimiliano Mazzone, Martin Guilliams, Jo A. Van Ginderachter
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Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/a203b2adbb4344c7be80bcf4c68f425a
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spelling oai:doaj.org-article:a203b2adbb4344c7be80bcf4c68f425a2021-12-02T14:38:56ZThe tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity10.1038/ncomms137202041-1723https://doaj.org/article/a203b2adbb4344c7be80bcf4c68f425a2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13720https://doaj.org/toc/2041-1723Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposing functions in regulating the anti-tumour immune response.Damya LaouiJiri KeirsseYannick MoriasEva Van OvermeireXenia GeeraertsYvon ElkrimMate KissEvangelia BolliQods LahmarDorine SichienJens SerneelsCharlotte L. ScottLouis BoonPatrick De BaetselierMassimiliano MazzoneMartin GuilliamsJo A. Van GinderachterNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Damya Laoui
Jiri Keirsse
Yannick Morias
Eva Van Overmeire
Xenia Geeraerts
Yvon Elkrim
Mate Kiss
Evangelia Bolli
Qods Lahmar
Dorine Sichien
Jens Serneels
Charlotte L. Scott
Louis Boon
Patrick De Baetselier
Massimiliano Mazzone
Martin Guilliams
Jo A. Van Ginderachter
The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
description Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposing functions in regulating the anti-tumour immune response.
format article
author Damya Laoui
Jiri Keirsse
Yannick Morias
Eva Van Overmeire
Xenia Geeraerts
Yvon Elkrim
Mate Kiss
Evangelia Bolli
Qods Lahmar
Dorine Sichien
Jens Serneels
Charlotte L. Scott
Louis Boon
Patrick De Baetselier
Massimiliano Mazzone
Martin Guilliams
Jo A. Van Ginderachter
author_facet Damya Laoui
Jiri Keirsse
Yannick Morias
Eva Van Overmeire
Xenia Geeraerts
Yvon Elkrim
Mate Kiss
Evangelia Bolli
Qods Lahmar
Dorine Sichien
Jens Serneels
Charlotte L. Scott
Louis Boon
Patrick De Baetselier
Massimiliano Mazzone
Martin Guilliams
Jo A. Van Ginderachter
author_sort Damya Laoui
title The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
title_short The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
title_full The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
title_fullStr The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
title_full_unstemmed The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
title_sort tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/a203b2adbb4344c7be80bcf4c68f425a
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