Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging

Raman probes which operate in the cellular silent region are of interest for live cell imaging. Here, the authors report on the development of a water soluble polydiacetylene Raman probe with enhanced Raman signal in the silent region which can be functionalised for organelle targeting and demonstra...

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Bibliographic Details
Main Authors: Sidan Tian, Haozheng Li, Zhong Li, Huajun Tang, Mingming Yin, Yage Chen, Shun Wang, Yuting Gao, Xiangliang Yang, Fanling Meng, Joseph W. Lauher, Ping Wang, Liang Luo
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/a203bf546ca54b849c3c8ae8ef67ffc0
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Summary:Raman probes which operate in the cellular silent region are of interest for live cell imaging. Here, the authors report on the development of a water soluble polydiacetylene Raman probe with enhanced Raman signal in the silent region which can be functionalised for organelle targeting and demonstrate application.