Evaluation of at-home methods for N95 filtering facepiece respirator decontamination

Abstract N95 filtering facepiece respirators (FFRs) are essential for the protection of healthcare professionals and other high-risk groups against Coronavirus Disease of 2019 (COVID-19). In response to shortages in FFRs during the ongoing COVID-19 pandemic, the Food and Drug Administration issued a...

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Autores principales:	T. X. Chen, A. Pinharanda, N. A. Steinemann, K. Yasuma-Mitobe, E. Lee, J. Hahn, L. Wu, S. Fanourakis, D. S. Peterka, E. M. C. Hillman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a20b8cac8dce4b688080584019bce6c5
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spelling	oai:doaj.org-article:a20b8cac8dce4b688080584019bce6c52021-12-02T18:37:12ZEvaluation of at-home methods for N95 filtering facepiece respirator decontamination10.1038/s41598-021-99129-82045-2322https://doaj.org/article/a20b8cac8dce4b688080584019bce6c52021-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-99129-8https://doaj.org/toc/2045-2322Abstract N95 filtering facepiece respirators (FFRs) are essential for the protection of healthcare professionals and other high-risk groups against Coronavirus Disease of 2019 (COVID-19). In response to shortages in FFRs during the ongoing COVID-19 pandemic, the Food and Drug Administration issued an Emergency Use Authorization permitting FFR decontamination and reuse. However, although industrial decontamination services are available at some large institutions, FFR decontamination is not widely accessible. To be effective, FFR decontamination must (1) inactivate the virus; (2) preserve FFR integrity, specifically fit and filtering capability; and (3) be non-toxic and safe. Here we identify and test at-home heat-based methods for FFR decontamination that meet these requirements using common household appliances. Our results identify potential protocols for simple and accessible FFR decontamination, while also highlighting unsuitable methods that may jeopardize FFR integrity.T. X. ChenA. PinharandaN. A. SteinemannK. Yasuma-MitobeE. LeeJ. HahnL. WuS. FanourakisD. S. PeterkaE. M. C. HillmanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q T. X. Chen A. Pinharanda N. A. Steinemann K. Yasuma-Mitobe E. Lee J. Hahn L. Wu S. Fanourakis D. S. Peterka E. M. C. Hillman Evaluation of at-home methods for N95 filtering facepiece respirator decontamination
description	Abstract N95 filtering facepiece respirators (FFRs) are essential for the protection of healthcare professionals and other high-risk groups against Coronavirus Disease of 2019 (COVID-19). In response to shortages in FFRs during the ongoing COVID-19 pandemic, the Food and Drug Administration issued an Emergency Use Authorization permitting FFR decontamination and reuse. However, although industrial decontamination services are available at some large institutions, FFR decontamination is not widely accessible. To be effective, FFR decontamination must (1) inactivate the virus; (2) preserve FFR integrity, specifically fit and filtering capability; and (3) be non-toxic and safe. Here we identify and test at-home heat-based methods for FFR decontamination that meet these requirements using common household appliances. Our results identify potential protocols for simple and accessible FFR decontamination, while also highlighting unsuitable methods that may jeopardize FFR integrity.
format	article
author	T. X. Chen A. Pinharanda N. A. Steinemann K. Yasuma-Mitobe E. Lee J. Hahn L. Wu S. Fanourakis D. S. Peterka E. M. C. Hillman
author_facet	T. X. Chen A. Pinharanda N. A. Steinemann K. Yasuma-Mitobe E. Lee J. Hahn L. Wu S. Fanourakis D. S. Peterka E. M. C. Hillman
author_sort	T. X. Chen
title	Evaluation of at-home methods for N95 filtering facepiece respirator decontamination
title_short	Evaluation of at-home methods for N95 filtering facepiece respirator decontamination
title_full	Evaluation of at-home methods for N95 filtering facepiece respirator decontamination
title_fullStr	Evaluation of at-home methods for N95 filtering facepiece respirator decontamination
title_full_unstemmed	Evaluation of at-home methods for N95 filtering facepiece respirator decontamination
title_sort	evaluation of at-home methods for n95 filtering facepiece respirator decontamination
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a20b8cac8dce4b688080584019bce6c5
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Evaluation of at-home methods for N95 filtering facepiece respirator decontamination

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