An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas

Strong transgene suppression has been observed in Chlamydomonas reinhardtii, but the underlying mechanism is unknown. Here, the authors identify a sirtuin-type histone deacetylase that selectively acts on transgenic DNA to repress gene expression by assembling a repressive chromatin structure compos...

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Autores principales: Juliane Neupert, Sean D. Gallaher, Yinghong Lu, Daniela Strenkert, Na’ama Segal, Rouhollah Barahimipour, Sorel T. Fitz-Gibbon, Michael Schroda, Sabeeha S. Merchant, Ralph Bock
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a20d8d3521784cf38c6e1a4183cbef92
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