Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics

Huang et al demonstrate that glioblastoma cells upregulate axon guidance molecule Plexin-B2 to gain invasiveness and that Plexin-B2 promotes glioblastoma cell infiltration along axon fiber tracts in intracranial transplant models by modulating cellular biomechanics.

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Bibliographic Details
Main Authors:	Yong Huang, Rut Tejero, Vivian K. Lee, Concetta Brusco, Theodore Hannah, Taylor B. Bertucci, Chrystian Junqueira Alves, Igor Katsyv, Michael Kluge, Ramsey Foty, Bin Zhang, Caroline C. Friedel, Guohao Dai, Hongyan Zou, Roland H. Friedel
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Biology (General) QH301-705.5
Online Access:	https://doaj.org/article/a21043ef77f3429eb2a9321d811b140e
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spelling	oai:doaj.org-article:a21043ef77f3429eb2a9321d811b140e2021-12-02T14:16:33ZPlexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics10.1038/s42003-021-01667-42399-3642https://doaj.org/article/a21043ef77f3429eb2a9321d811b140e2021-01-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01667-4https://doaj.org/toc/2399-3642Huang et al demonstrate that glioblastoma cells upregulate axon guidance molecule Plexin-B2 to gain invasiveness and that Plexin-B2 promotes glioblastoma cell infiltration along axon fiber tracts in intracranial transplant models by modulating cellular biomechanics.Yong HuangRut TejeroVivian K. LeeConcetta BruscoTheodore HannahTaylor B. BertucciChrystian Junqueira AlvesIgor KatsyvMichael KlugeRamsey FotyBin ZhangCaroline C. FriedelGuohao DaiHongyan ZouRoland H. FriedelNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Yong Huang Rut Tejero Vivian K. Lee Concetta Brusco Theodore Hannah Taylor B. Bertucci Chrystian Junqueira Alves Igor Katsyv Michael Kluge Ramsey Foty Bin Zhang Caroline C. Friedel Guohao Dai Hongyan Zou Roland H. Friedel Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
description	Huang et al demonstrate that glioblastoma cells upregulate axon guidance molecule Plexin-B2 to gain invasiveness and that Plexin-B2 promotes glioblastoma cell infiltration along axon fiber tracts in intracranial transplant models by modulating cellular biomechanics.
format	article
author	Yong Huang Rut Tejero Vivian K. Lee Concetta Brusco Theodore Hannah Taylor B. Bertucci Chrystian Junqueira Alves Igor Katsyv Michael Kluge Ramsey Foty Bin Zhang Caroline C. Friedel Guohao Dai Hongyan Zou Roland H. Friedel
author_facet	Yong Huang Rut Tejero Vivian K. Lee Concetta Brusco Theodore Hannah Taylor B. Bertucci Chrystian Junqueira Alves Igor Katsyv Michael Kluge Ramsey Foty Bin Zhang Caroline C. Friedel Guohao Dai Hongyan Zou Roland H. Friedel
author_sort	Yong Huang
title	Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
title_short	Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
title_full	Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
title_fullStr	Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
title_full_unstemmed	Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
title_sort	plexin-b2 facilitates glioblastoma infiltration by modulating cell biomechanics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a21043ef77f3429eb2a9321d811b140e
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Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics

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