Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

Dietary extracellular vesicles (EVs) could potentially be absorbed by the intestinal tract of the host and exert multiple phenotypic changes. Here, the authors isolate and characterize EVs from raw and commercial bovine milk and show orally administered EVs to have a context specific role in promoti...

Full description

Saved in:
Bibliographic Details
Main Authors: Monisha Samuel, Pamali Fonseka, Rahul Sanwlani, Lahiru Gangoda, Sing Ho Chee, Shivakumar Keerthikumar, Alex Spurling, Sai V. Chitti, Damien Zanker, Ching-Seng Ang, Ishara Atukorala, Taeyoung Kang, Sanjay Shahi, Akbar L. Marzan, Christina Nedeva, Claire Vennin, Morghan C. Lucas, Lesley Cheng, David Herrmann, Mohashin Pathan, David Chisanga, Sean C. Warren, Kening Zhao, Nidhi Abraham, Sushma Anand, Stephanie Boukouris, Christopher G. Adda, Lanzhou Jiang, Tanmay M. Shekhar, Nikola Baschuk, Christine J. Hawkins, Amelia J. Johnston, Jacqueline Monique Orian, Nicholas J. Hoogenraad, Ivan K. Poon, Andrew F. Hill, Markandeya Jois, Paul Timpson, Belinda S. Parker, Suresh Mathivanan
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/a210d2d7abd146b99318109f85a7d355
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items