A quasi-integral controller for adaptation of genetic modules to variable ribosome demand

Competition for shared cellular resources often renders genetic circuits poorly predictable. Here the authors design a biomolecular quasi-integral controller that allows gene expression to adapt to variable demand in translation resources.

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Detalles Bibliográficos
Autores principales: Hsin-Ho Huang, Yili Qian, Domitilla Del Vecchio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/a21277718beb4c2d8c7c9d40cb7e1f5f
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