Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

How the Drosophila lymph gland hemocytes develop and are regulated at a single-cell level is unclear. Here, the authors use single-cell RNA sequencing to show heterogeneity of developing hemocytes in the lymph gland and how they react to wasp infestation, and compare hemocytes from two independent o...

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Autores principales: Bumsik Cho, Sang-Ho Yoon, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Daehan Lee, A. Vipin Menon, Seok Jun Moon, Norbert Perrimon, Jin-Wu Nam, Jiwon Shim
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a217d9fbf42943298b9152638532fa93
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spelling oai:doaj.org-article:a217d9fbf42943298b9152638532fa932021-12-02T17:19:41ZSingle-cell transcriptome maps of myeloid blood cell lineages in Drosophila10.1038/s41467-020-18135-y2041-1723https://doaj.org/article/a217d9fbf42943298b9152638532fa932020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18135-yhttps://doaj.org/toc/2041-1723How the Drosophila lymph gland hemocytes develop and are regulated at a single-cell level is unclear. Here, the authors use single-cell RNA sequencing to show heterogeneity of developing hemocytes in the lymph gland and how they react to wasp infestation, and compare hemocytes from two independent origins.Bumsik ChoSang-Ho YoonDaewon LeeFerdinand KorantengSudhir Gopal TattikotaNuri ChaMingyu ShinHobin DoYanhui HuSue Young OhDaehan LeeA. Vipin MenonSeok Jun MoonNorbert PerrimonJin-Wu NamJiwon ShimNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bumsik Cho
Sang-Ho Yoon
Daewon Lee
Ferdinand Koranteng
Sudhir Gopal Tattikota
Nuri Cha
Mingyu Shin
Hobin Do
Yanhui Hu
Sue Young Oh
Daehan Lee
A. Vipin Menon
Seok Jun Moon
Norbert Perrimon
Jin-Wu Nam
Jiwon Shim
Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
description How the Drosophila lymph gland hemocytes develop and are regulated at a single-cell level is unclear. Here, the authors use single-cell RNA sequencing to show heterogeneity of developing hemocytes in the lymph gland and how they react to wasp infestation, and compare hemocytes from two independent origins.
format article
author Bumsik Cho
Sang-Ho Yoon
Daewon Lee
Ferdinand Koranteng
Sudhir Gopal Tattikota
Nuri Cha
Mingyu Shin
Hobin Do
Yanhui Hu
Sue Young Oh
Daehan Lee
A. Vipin Menon
Seok Jun Moon
Norbert Perrimon
Jin-Wu Nam
Jiwon Shim
author_facet Bumsik Cho
Sang-Ho Yoon
Daewon Lee
Ferdinand Koranteng
Sudhir Gopal Tattikota
Nuri Cha
Mingyu Shin
Hobin Do
Yanhui Hu
Sue Young Oh
Daehan Lee
A. Vipin Menon
Seok Jun Moon
Norbert Perrimon
Jin-Wu Nam
Jiwon Shim
author_sort Bumsik Cho
title Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_short Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_full Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_fullStr Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_full_unstemmed Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
title_sort single-cell transcriptome maps of myeloid blood cell lineages in drosophila
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a217d9fbf42943298b9152638532fa93
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