STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS

The changes of the cytokines and lipidic spectrum at experimental hyperlipoidemia and arterial hypertensia was made at 20 rats «Vistar» during 6 months. As the material of research was the blood serum. The cytokines was made by the method solid-phase not competitive immune-enzyme analysis with the u...

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Autores principales:	E. P. Turmova, A. A. Grigoryuk, E. A. Bichkov, E. V. Markelova, I. V. Chihkalovets
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	atherosclerosis hyperlipoidemia cytokines rats Science Q
Acceso en línea:	https://doaj.org/article/a2185eadb2a34ae59931885446b9f837
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spelling	oai:doaj.org-article:a2185eadb2a34ae59931885446b9f8372021-11-23T06:14:20ZSTUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS2541-94202587-9596https://doaj.org/article/a2185eadb2a34ae59931885446b9f8372012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/945https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The changes of the cytokines and lipidic spectrum at experimental hyperlipoidemia and arterial hypertensia was made at 20 rats «Vistar» during 6 months. As the material of research was the blood serum. The cytokines was made by the method solid-phase not competitive immune-enzyme analysis with the use of sets: Rat «R&D Diagnostics Inc.», USA. The content of the general cholesterol; triglycerides; LDL; HDL was investigated by the method of standard colorimetric analysis with the use of reagents «Olveks diagnosticum» (Russia). The increasing of the general cholesterol, LDL; HDL, atherogenic coefficient, IFN-γ and IL-1β in blood of animals was revealed. At application of immunomodulator «Galavit» at experimental atherosclerosis the decreasing contains of IL-1, IFN-γ, the level of general cholesterol; LDL; HDL, atherogenic coefficient is fixed.E. P. TurmovaA. A. GrigoryukE. A. BichkovE. V. MarkelovaI. V. ChihkalovetsScientific Сentre for Family Health and Human Reproduction ProblemsarticleatherosclerosishyperlipoidemiacytokinesratsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 323-326 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	atherosclerosis hyperlipoidemia cytokines rats Science Q
spellingShingle	atherosclerosis hyperlipoidemia cytokines rats Science Q E. P. Turmova A. A. Grigoryuk E. A. Bichkov E. V. Markelova I. V. Chihkalovets STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS
description	The changes of the cytokines and lipidic spectrum at experimental hyperlipoidemia and arterial hypertensia was made at 20 rats «Vistar» during 6 months. As the material of research was the blood serum. The cytokines was made by the method solid-phase not competitive immune-enzyme analysis with the use of sets: Rat «R&D Diagnostics Inc.», USA. The content of the general cholesterol; triglycerides; LDL; HDL was investigated by the method of standard colorimetric analysis with the use of reagents «Olveks diagnosticum» (Russia). The increasing of the general cholesterol, LDL; HDL, atherogenic coefficient, IFN-γ and IL-1β in blood of animals was revealed. At application of immunomodulator «Galavit» at experimental atherosclerosis the decreasing contains of IL-1, IFN-γ, the level of general cholesterol; LDL; HDL, atherogenic coefficient is fixed.
format	article
author	E. P. Turmova A. A. Grigoryuk E. A. Bichkov E. V. Markelova I. V. Chihkalovets
author_facet	E. P. Turmova A. A. Grigoryuk E. A. Bichkov E. V. Markelova I. V. Chihkalovets
author_sort	E. P. Turmova
title	STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS
title_short	STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS
title_full	STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS
title_fullStr	STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS
title_full_unstemmed	STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS
title_sort	studying of application immunomodulator «galavit» at experimental atherosclerosis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/a2185eadb2a34ae59931885446b9f837
work_keys_str_mv	AT epturmova studyingofapplicationimmunomodulatorgalavitatexperimentalatherosclerosis AT aagrigoryuk studyingofapplicationimmunomodulatorgalavitatexperimentalatherosclerosis AT eabichkov studyingofapplicationimmunomodulatorgalavitatexperimentalatherosclerosis AT evmarkelova studyingofapplicationimmunomodulatorgalavitatexperimentalatherosclerosis AT ivchihkalovets studyingofapplicationimmunomodulatorgalavitatexperimentalatherosclerosis
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STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS

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