Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy

Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy

Glycolipids are glycoconjugates with important biological functions, but techniques for their analysis are deficient. Here, the authors report the use of cryogenic gas-phase infrared spectroscopy to investigate isomerism in a set of immunologically relevant glycolipids, and show that their structura...

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Autores principales: Carla Kirschbaum, Kim Greis, Eike Mucha, Lisa Kain, Shenglou Deng, Andreas Zappe, Sandy Gewinner, Wieland Schöllkopf, Gert von Helden, Gerard Meijer, Paul B. Savage, Mateusz Marianski, Luc Teyton, Kevin Pagel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a21a464c5dbd442ba4a70c62e515703b
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spelling oai:doaj.org-article:a21a464c5dbd442ba4a70c62e515703b2021-12-02T11:02:37ZUnravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy10.1038/s41467-021-21480-12041-1723https://doaj.org/article/a21a464c5dbd442ba4a70c62e515703b2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21480-1https://doaj.org/toc/2041-1723Glycolipids are glycoconjugates with important biological functions, but techniques for their analysis are deficient. Here, the authors report the use of cryogenic gas-phase infrared spectroscopy to investigate isomerism in a set of immunologically relevant glycolipids, and show that their structural features can be accurately resolved based on a narrow spectral fingerprint region.Carla KirschbaumKim GreisEike MuchaLisa KainShenglou DengAndreas ZappeSandy GewinnerWieland SchöllkopfGert von HeldenGerard MeijerPaul B. SavageMateusz MarianskiLuc TeytonKevin PagelNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carla Kirschbaum
Kim Greis
Eike Mucha
Lisa Kain
Shenglou Deng
Andreas Zappe
Sandy Gewinner
Wieland Schöllkopf
Gert von Helden
Gerard Meijer
Paul B. Savage
Mateusz Marianski
Luc Teyton
Kevin Pagel
Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy
description Glycolipids are glycoconjugates with important biological functions, but techniques for their analysis are deficient. Here, the authors report the use of cryogenic gas-phase infrared spectroscopy to investigate isomerism in a set of immunologically relevant glycolipids, and show that their structural features can be accurately resolved based on a narrow spectral fingerprint region.
format article
author Carla Kirschbaum
Kim Greis
Eike Mucha
Lisa Kain
Shenglou Deng
Andreas Zappe
Sandy Gewinner
Wieland Schöllkopf
Gert von Helden
Gerard Meijer
Paul B. Savage
Mateusz Marianski
Luc Teyton
Kevin Pagel
author_facet Carla Kirschbaum
Kim Greis
Eike Mucha
Lisa Kain
Shenglou Deng
Andreas Zappe
Sandy Gewinner
Wieland Schöllkopf
Gert von Helden
Gerard Meijer
Paul B. Savage
Mateusz Marianski
Luc Teyton
Kevin Pagel
author_sort Carla Kirschbaum
title Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy
title_short Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy
title_full Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy
title_fullStr Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy
title_full_unstemmed Unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy
title_sort unravelling the structural complexity of glycolipids with cryogenic infrared spectroscopy
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a21a464c5dbd442ba4a70c62e515703b
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