Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium

Objective: One of the most important duties of an anesthetist is keeping the airways open. Since there is a contraindication of succinylcholine in some cases, tracheal intubation is done by non-depolarization muscle relaxants with a delay of 4 min. In this study, this delay time has been decreased t...

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Autores principales:	M Matloub, SM Rabiei, M Mir
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2001
Materias:	induction of anesthesia tracheal intubation hemodynamic changes ett tolerance Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a2213768a4c44bc7bdb7d12720c6d414
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spelling	oai:doaj.org-article:a2213768a4c44bc7bdb7d12720c6d4142021-11-10T09:21:13ZEarly tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium1561-41072251-7170https://doaj.org/article/a2213768a4c44bc7bdb7d12720c6d4142001-10-01T00:00:00Zhttp://jbums.org/article-1-2850-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: One of the most important duties of an anesthetist is keeping the airways open. Since there is a contraindication of succinylcholine in some cases, tracheal intubation is done by non-depolarization muscle relaxants with a delay of 4 min. In this study, this delay time has been decreased to 30 seconds with an additional dose of thiopental (20%) and atracorium injection. Methods: This study was conducted on 100 cases in ASA class I of American society of anesthesiologists classification with patients of 15-45 years of age. They were randomly divided into two groups (Each group with 50 cases). In control group after premedication, in first group anesthesia started with atracorium (0.6 mg/kg) and then with thiopental sodium (5 mg/kg) and intubation was done after 4 min of ventilation. In case group after administration of the same premedication and atracorium, an additional dose of thiopental sodium (20%) was injected and tracheal intubation was done after 30 seconds. Heartbeat and blood pressure at 0 minute after premedication, at induction of anesthesia and tracheal intubation and after 5 min with intubation were monitored. The quality and tube tolerance were recorded and analyzed statistically as well. Findings: In both groups after induction of anesthesia, systolic and diastolic blood pressure decreased and heart rate increased. In spite of changes of blood pressure in case group, there was not a statistically significant difference. Intubation was easily performed on 92% of patients in case group and 96% in control group and also 20% in case group and 12% in control group did not tolerate the endotracheal tube without any significant difference. Conclusion: A 4-minute delay for intubation by atracorium can be decreased to 30 seconds with an additional dose of thiopental. This method can be used for patients with contraindication of succinylcholine use and also it can decrease the side effects of longtime PPV mask ventilation and anesthesia bag.M MatloubSM RabieiM MirBabol University of Medical Sciencesarticleinduction of anesthesiatracheal intubationhemodynamic changesett toleranceMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 3, Iss 4, Pp 29-32 (2001)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	induction of anesthesia tracheal intubation hemodynamic changes ett tolerance Medicine R Medicine (General) R5-920
spellingShingle	induction of anesthesia tracheal intubation hemodynamic changes ett tolerance Medicine R Medicine (General) R5-920 M Matloub SM Rabiei M Mir Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium
description	Objective: One of the most important duties of an anesthetist is keeping the airways open. Since there is a contraindication of succinylcholine in some cases, tracheal intubation is done by non-depolarization muscle relaxants with a delay of 4 min. In this study, this delay time has been decreased to 30 seconds with an additional dose of thiopental (20%) and atracorium injection. Methods: This study was conducted on 100 cases in ASA class I of American society of anesthesiologists classification with patients of 15-45 years of age. They were randomly divided into two groups (Each group with 50 cases). In control group after premedication, in first group anesthesia started with atracorium (0.6 mg/kg) and then with thiopental sodium (5 mg/kg) and intubation was done after 4 min of ventilation. In case group after administration of the same premedication and atracorium, an additional dose of thiopental sodium (20%) was injected and tracheal intubation was done after 30 seconds. Heartbeat and blood pressure at 0 minute after premedication, at induction of anesthesia and tracheal intubation and after 5 min with intubation were monitored. The quality and tube tolerance were recorded and analyzed statistically as well. Findings: In both groups after induction of anesthesia, systolic and diastolic blood pressure decreased and heart rate increased. In spite of changes of blood pressure in case group, there was not a statistically significant difference. Intubation was easily performed on 92% of patients in case group and 96% in control group and also 20% in case group and 12% in control group did not tolerate the endotracheal tube without any significant difference. Conclusion: A 4-minute delay for intubation by atracorium can be decreased to 30 seconds with an additional dose of thiopental. This method can be used for patients with contraindication of succinylcholine use and also it can decrease the side effects of longtime PPV mask ventilation and anesthesia bag.
format	article
author	M Matloub SM Rabiei M Mir
author_facet	M Matloub SM Rabiei M Mir
author_sort	M Matloub
title	Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium
title_short	Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium
title_full	Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium
title_fullStr	Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium
title_full_unstemmed	Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium
title_sort	early tracheal intubation with non-depolarization muscle relaxants and additional dose of thiopental sodium
publisher	Babol University of Medical Sciences
publishDate	2001
url	https://doaj.org/article/a2213768a4c44bc7bdb7d12720c6d414
work_keys_str_mv	AT mmatloub earlytrachealintubationwithnondepolarizationmusclerelaxantsandadditionaldoseofthiopentalsodium AT smrabiei earlytrachealintubationwithnondepolarizationmusclerelaxantsandadditionaldoseofthiopentalsodium AT mmir earlytrachealintubationwithnondepolarizationmusclerelaxantsandadditionaldoseofthiopentalsodium
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Early tracheal intubation with non-depolarization muscle relaxants and additional dose of Thiopental Sodium

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