The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins

ABSTRACT Type I interferon (IFN)-stimulated genes (ISGs) have critical roles in inhibiting virus replication and dissemination. Despite advances in understanding the molecular basis of ISG restriction, the antiviral mechanisms of many remain unclear. The 20-kDa ISG ISG20 is a nuclear 3′–5′ exonuclea...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Christopher M. Weiss, Derek W. Trobaugh, Chengqun Sun, Tiffany M. Lucas, Michael S. Diamond, Kate D. Ryman, William B. Klimstra
Format: article
Langue:EN
Publié: American Society for Microbiology 2018
Sujets:
Accès en ligne:https://doaj.org/article/a2287e9b9d7344b2a42e47c800dea8d0
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!