The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension
Survival and proliferation of vascular cells in the presence of DNA damage is a characteristic of pulmonary arterial hypertension. Here the authors show that the phosphatase EYA3 contributes to vascular remodeling by promoting survival of damaged cells, and present results of genetic and pharmacolog...
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Autores principales: | Yuhua Wang, Ram Naresh Pandey, Allen J. York, Jaya Mallela, William C. Nichols, Yueh-Chiang Hu, Jeffery D. Molkentin, Kathryn A. Wikenheiser-Brokamp, Rashmi S. Hegde |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/a22dbf3a31634184aa871160e2f3a493 |
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