A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity

A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity

Abstract Protein kinase B (PknB) is one of the Mycobacterium tuberculosis serine/threonine protein kinases and has an essential role in sustaining mycobacterial growth. Here, we identified and characterized a novel small molecule compound named IMB-YH-8 that inhibited PknB and served as anti-mycobac...

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Autores principales: Jian Xu, Ju-xian Wang, Jin-ming Zhou, Chang-liang Xu, Bin Huang, Yun Xing, Bin Wang, Rui Luo, Yu-cheng Wang, Xue-fu You, Yu Lu, Li-yan Yu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a22e2ae045844aef9db204f3b1fa9c74
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