Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.

Acquisition of nasal Staphylococcus aureus (S. aureus) colonization by contaminated hands is likely an important determinant of its nasal carriage rate in health care and lab setting. The objective of our cross-sectional study was to assess the prevalence of nasal methicillin-sensitive (MSSA) or -re...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mitra Saadatian-Elahi, Anne Tristan, Frédéric Laurent, Jean-Philippe Rasigade, Coralie Bouchiat, Anne-Gaëlle Ranc, Gérard Lina, Olivier Dauwalder, Jérôme Etienne, Michèle Bes, François Vandenesch
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a2323738aa9542f2899b2c7857a56ca6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a2323738aa9542f2899b2c7857a56ca6
record_format	dspace
spelling	oai:doaj.org-article:a2323738aa9542f2899b2c7857a56ca62021-11-18T08:41:20ZBasic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.1932-620310.1371/journal.pone.0082851https://doaj.org/article/a2323738aa9542f2899b2c7857a56ca62013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24367562/?tool=EBIhttps://doaj.org/toc/1932-6203Acquisition of nasal Staphylococcus aureus (S. aureus) colonization by contaminated hands is likely an important determinant of its nasal carriage rate in health care and lab setting. The objective of our cross-sectional study was to assess the prevalence of nasal methicillin-sensitive (MSSA) or -resistant Staphylococcus aureus (MRSA) carriage among health care professionals (HCPs) attending an international symposium and to study the association between compliance with hygiene rules, individual-related parameters, and medical conditions with nasal S. aureus carriage in this population. After obtaining consent, two nasal swabs were collected. Nasal MSSA and MRSA carriage was measured by the: i) molecular approach targeting spa, mecA and mecA-orfX junction sequences, and ii) culture on selective S. aureus media combined with mecA molecular detection of isolated strains. Information on compliance with hygiene rules, demographic variables, sector of activity and long-term medication was collected by anonymous questionnaire. The participation rate was 32.3%. In total, 176 subjects from 34 countries were included in the analysis. S. aureus was isolated from the nasal swabs of 57 (32.4%) subjects, of whom 3 (5.3%) harbored MRSA strains. Overall, 123 subjects reported working in microbiology laboratories with direct manipulation of S. aureus, and 29 acknowledged regular contacts with patients. In this exposed population, hydro-alcoholic solutions appeared to have a significant protective effect against nasal S. aureus carriage (OR = 0.36; 95% CI: 0.15-0.85). Hospital work was associated with increased risk of nasal S. aureus carriage (OR = 2.38; 95% CI: 1.07-5.29). The results of this study showed that compliance with basic rules of hygiene, such as the use of hydro-alcoholic solutions, could reduce the risk of nasal S. aureus colonization. Hydro-alcoholic solution could interrupt auto-transmission of the pathogen, consequently decreasing the overall nasal carriage rate, specifically in transient carriers.Mitra Saadatian-ElahiAnne TristanFrédéric LaurentJean-Philippe RasigadeCoralie BouchiatAnne-Gaëlle RancGérard LinaOlivier DauwalderJérôme EtienneMichèle BesFrançois VandeneschPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 12, p e82851 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mitra Saadatian-Elahi Anne Tristan Frédéric Laurent Jean-Philippe Rasigade Coralie Bouchiat Anne-Gaëlle Ranc Gérard Lina Olivier Dauwalder Jérôme Etienne Michèle Bes François Vandenesch Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.
description	Acquisition of nasal Staphylococcus aureus (S. aureus) colonization by contaminated hands is likely an important determinant of its nasal carriage rate in health care and lab setting. The objective of our cross-sectional study was to assess the prevalence of nasal methicillin-sensitive (MSSA) or -resistant Staphylococcus aureus (MRSA) carriage among health care professionals (HCPs) attending an international symposium and to study the association between compliance with hygiene rules, individual-related parameters, and medical conditions with nasal S. aureus carriage in this population. After obtaining consent, two nasal swabs were collected. Nasal MSSA and MRSA carriage was measured by the: i) molecular approach targeting spa, mecA and mecA-orfX junction sequences, and ii) culture on selective S. aureus media combined with mecA molecular detection of isolated strains. Information on compliance with hygiene rules, demographic variables, sector of activity and long-term medication was collected by anonymous questionnaire. The participation rate was 32.3%. In total, 176 subjects from 34 countries were included in the analysis. S. aureus was isolated from the nasal swabs of 57 (32.4%) subjects, of whom 3 (5.3%) harbored MRSA strains. Overall, 123 subjects reported working in microbiology laboratories with direct manipulation of S. aureus, and 29 acknowledged regular contacts with patients. In this exposed population, hydro-alcoholic solutions appeared to have a significant protective effect against nasal S. aureus carriage (OR = 0.36; 95% CI: 0.15-0.85). Hospital work was associated with increased risk of nasal S. aureus carriage (OR = 2.38; 95% CI: 1.07-5.29). The results of this study showed that compliance with basic rules of hygiene, such as the use of hydro-alcoholic solutions, could reduce the risk of nasal S. aureus colonization. Hydro-alcoholic solution could interrupt auto-transmission of the pathogen, consequently decreasing the overall nasal carriage rate, specifically in transient carriers.
format	article
author	Mitra Saadatian-Elahi Anne Tristan Frédéric Laurent Jean-Philippe Rasigade Coralie Bouchiat Anne-Gaëlle Ranc Gérard Lina Olivier Dauwalder Jérôme Etienne Michèle Bes François Vandenesch
author_facet	Mitra Saadatian-Elahi Anne Tristan Frédéric Laurent Jean-Philippe Rasigade Coralie Bouchiat Anne-Gaëlle Ranc Gérard Lina Olivier Dauwalder Jérôme Etienne Michèle Bes François Vandenesch
author_sort	Mitra Saadatian-Elahi
title	Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.
title_short	Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.
title_full	Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.
title_fullStr	Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.
title_full_unstemmed	Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.
title_sort	basic rules of hygiene protect health care and lab workers from nasal colonization by staphylococcus aureus: an international cross-sectional study.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/a2323738aa9542f2899b2c7857a56ca6
work_keys_str_mv	AT mitrasaadatianelahi basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT annetristan basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT fredericlaurent basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT jeanphilipperasigade basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT coraliebouchiat basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT annegaelleranc basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT gerardlina basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT olivierdauwalder basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT jeromeetienne basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT michelebes basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy AT francoisvandenesch basicrulesofhygieneprotecthealthcareandlabworkersfromnasalcolonizationbystaphylococcusaureusaninternationalcrosssectionalstudy
_version_	1718421461549449216

Basic rules of hygiene protect health care and lab workers from nasal colonization by Staphylococcus aureus: an international cross-sectional study.

Ejemplares similares