Molecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoni.
Cys-loop ligand-gated ion channels (LGICs) mediate fast ionotropic neurotransmission. They are proven drug targets in nematodes and arthropods, but are poorly characterized in flatworms. In this study, we characterized the anion-selective, non-acetylcholine-gated Cys-loop LGICs from Schistosoma mans...
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Autores principales: | Vanessa Dufour, Robin N Beech, Claudia Wever, Joseph A Dent, Timothy G Geary |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/a233d3aff8dd4063bde55c97eecca554 |
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