Molecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoni.

Cys-loop ligand-gated ion channels (LGICs) mediate fast ionotropic neurotransmission. They are proven drug targets in nematodes and arthropods, but are poorly characterized in flatworms. In this study, we characterized the anion-selective, non-acetylcholine-gated Cys-loop LGICs from Schistosoma mans...

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Autores principales: Vanessa Dufour, Robin N Beech, Claudia Wever, Joseph A Dent, Timothy G Geary
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a233d3aff8dd4063bde55c97eecca554
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