Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism

Bacterial protein FtsZ polymerizes at mid-cell and exhibits treadmilling dynamics, driving the movement of enzymes that synthesize septal peptidoglycan. Here, McCausland et al. combine theoretical modelling with single-molecule imaging of bacteria to show that FtsZ treadmilling drives enzyme movemen...

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Bibliographic Details
Main Authors: Joshua W. McCausland, Xinxing Yang, Georgia R. Squyres, Zhixin Lyu, Kevin E. Bruce, Melissa M. Lamanna, Bill Söderström, Ethan C. Garner, Malcolm E. Winkler, Jie Xiao, Jian Liu
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/a23599fc4d5a4c45aa6e7629aef838ab
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