DNase γ is the effector endonuclease for internucleosomal DNA fragmentation in necrosis.

DNase γ is the effector endonuclease for internucleosomal DNA fragmentation in necrosis.

Apoptosis and necrosis, two major forms of cell death, can be distinguished morphologically and biochemically. Internucleosomal DNA fragmentation (INDF) is a biochemical hallmark of apoptosis, and caspase-activated DNase (CAD), also known as DNA fragmentation factor 40 kDa (DFF40), is one of the maj...

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Autores principales: Ryushin Mizuta, Shinsuke Araki, Makoto Furukawa, Yuki Furukawa, Syota Ebara, Daisuke Shiokawa, Katsuhiko Hayashi, Sei-ichi Tanuma, Daisuke Kitamura
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/a23727df6fcc41cfba0a04177ec0ccc6
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