HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS

Absract. The data are presented that concern the levels of IL-1 receptor antagonist (IL-1 Ra) in blood serum of twenty-five patients with severe surgical sepsis. Sixteen patients recovered from the condition, whereas lethal outcome was registered in nine cases. The study was performed by means of im...

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Autores principales: V. V. Grebenyuk, G. A. Makarova, N. V. Yusan
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Lenguaje:RU
Publicado: SPb RAACI 2014
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spelling oai:doaj.org-article:a243c5e80256459daf478412a589984b2021-11-18T08:03:40ZHIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS1563-06252313-741X10.15789/1563-0625-2009-2-3-287-288https://doaj.org/article/a243c5e80256459daf478412a589984b2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/323https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbsract. The data are presented that concern the levels of IL-1 receptor antagonist (IL-1 Ra) in blood serum of twenty-five patients with severe surgical sepsis. Sixteen patients recovered from the condition, whereas lethal outcome was registered in nine cases. The study was performed by means of immunoassay, using «IFA-Best IL-1 Ra» kits supplied by the Vector-Best firm. Only three patients showed IL-1 Ra contents within normal limits, whereas others exhibited marked increase in IL-1 Ra levels, up to a mean of 2443.656±382.85 pg/ml (normal range, 50 to 1000 pg/ml).V. V. GrebenyukG. A. MakarovaN. V. YusanSPb RAACIarticlesurgical sepsisil-1 raelisalethal outcomeImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 11, Iss 2-3, Pp 287-288 (2014)
institution DOAJ
collection DOAJ
language RU
topic surgical sepsis
il-1 ra
elisa
lethal outcome
Immunologic diseases. Allergy
RC581-607
spellingShingle surgical sepsis
il-1 ra
elisa
lethal outcome
Immunologic diseases. Allergy
RC581-607
V. V. Grebenyuk
G. A. Makarova
N. V. Yusan
HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
description Absract. The data are presented that concern the levels of IL-1 receptor antagonist (IL-1 Ra) in blood serum of twenty-five patients with severe surgical sepsis. Sixteen patients recovered from the condition, whereas lethal outcome was registered in nine cases. The study was performed by means of immunoassay, using «IFA-Best IL-1 Ra» kits supplied by the Vector-Best firm. Only three patients showed IL-1 Ra contents within normal limits, whereas others exhibited marked increase in IL-1 Ra levels, up to a mean of 2443.656±382.85 pg/ml (normal range, 50 to 1000 pg/ml).
format article
author V. V. Grebenyuk
G. A. Makarova
N. V. Yusan
author_facet V. V. Grebenyuk
G. A. Makarova
N. V. Yusan
author_sort V. V. Grebenyuk
title HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
title_short HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
title_full HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
title_fullStr HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
title_full_unstemmed HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
title_sort high level of il -1 receptor antagonist as a lethality factor in patients with surgical sepsis
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/a243c5e80256459daf478412a589984b
work_keys_str_mv AT vvgrebenyuk highlevelofil1receptorantagonistasalethalityfactorinpatientswithsurgicalsepsis
AT gamakarova highlevelofil1receptorantagonistasalethalityfactorinpatientswithsurgicalsepsis
AT nvyusan highlevelofil1receptorantagonistasalethalityfactorinpatientswithsurgicalsepsis
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