Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.

<h4>Aim</h4>To assess the performance of automated disease detection in diabetic retinopathy screening using two field mydriatic photography.<h4>Methods</h4>Images from 8,271 sequential patient screening episodes from a South London diabetic retinopathy screening service were...

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Autores principales: Keith Goatman, Amanda Charnley, Laura Webster, Stephen Nussey
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Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/a249b448014a432a8b9449a60a98591a
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spelling oai:doaj.org-article:a249b448014a432a8b9449a60a98591a2021-11-18T07:32:47ZAssessment of automated disease detection in diabetic retinopathy screening using two-field photography.1932-620310.1371/journal.pone.0027524https://doaj.org/article/a249b448014a432a8b9449a60a98591a2011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174741/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Aim</h4>To assess the performance of automated disease detection in diabetic retinopathy screening using two field mydriatic photography.<h4>Methods</h4>Images from 8,271 sequential patient screening episodes from a South London diabetic retinopathy screening service were processed by the Medalytix iGrading™ automated grading system. For each screening episode macular-centred and disc-centred images of both eyes were acquired and independently graded according to the English national grading scheme. Where discrepancies were found between the automated result and original manual grade, internal and external arbitration was used to determine the final study grades. Two versions of the software were used: one that detected microaneurysms alone, and one that detected blot haemorrhages and exudates in addition to microaneurysms. Results for each version were calculated once using both fields and once using the macula-centred field alone.<h4>Results</h4>Of the 8,271 episodes, 346 (4.2%) were considered unassessable. Referable disease was detected in 587 episodes (7.1%). The sensitivity of the automated system for detecting unassessable images ranged from 97.4% to 99.1% depending on configuration. The sensitivity of the automated system for referable episodes ranged from 98.3% to 99.3%. All the episodes that included proliferative or pre-proliferative retinopathy were detected by the automated system regardless of configuration (192/192, 95% confidence interval 98.0% to 100%). If implemented as the first step in grading, the automated system would have reduced the manual grading effort by between 2,183 and 3,147 patient episodes (26.4% to 38.1%).<h4>Conclusion</h4>Automated grading can safely reduce the workload of manual grading using two field, mydriatic photography in a routine screening service.Keith GoatmanAmanda CharnleyLaura WebsterStephen NusseyPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 12, p e27524 (2011)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Keith Goatman
Amanda Charnley
Laura Webster
Stephen Nussey
Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.
description <h4>Aim</h4>To assess the performance of automated disease detection in diabetic retinopathy screening using two field mydriatic photography.<h4>Methods</h4>Images from 8,271 sequential patient screening episodes from a South London diabetic retinopathy screening service were processed by the Medalytix iGrading™ automated grading system. For each screening episode macular-centred and disc-centred images of both eyes were acquired and independently graded according to the English national grading scheme. Where discrepancies were found between the automated result and original manual grade, internal and external arbitration was used to determine the final study grades. Two versions of the software were used: one that detected microaneurysms alone, and one that detected blot haemorrhages and exudates in addition to microaneurysms. Results for each version were calculated once using both fields and once using the macula-centred field alone.<h4>Results</h4>Of the 8,271 episodes, 346 (4.2%) were considered unassessable. Referable disease was detected in 587 episodes (7.1%). The sensitivity of the automated system for detecting unassessable images ranged from 97.4% to 99.1% depending on configuration. The sensitivity of the automated system for referable episodes ranged from 98.3% to 99.3%. All the episodes that included proliferative or pre-proliferative retinopathy were detected by the automated system regardless of configuration (192/192, 95% confidence interval 98.0% to 100%). If implemented as the first step in grading, the automated system would have reduced the manual grading effort by between 2,183 and 3,147 patient episodes (26.4% to 38.1%).<h4>Conclusion</h4>Automated grading can safely reduce the workload of manual grading using two field, mydriatic photography in a routine screening service.
format article
author Keith Goatman
Amanda Charnley
Laura Webster
Stephen Nussey
author_facet Keith Goatman
Amanda Charnley
Laura Webster
Stephen Nussey
author_sort Keith Goatman
title Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.
title_short Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.
title_full Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.
title_fullStr Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.
title_full_unstemmed Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.
title_sort assessment of automated disease detection in diabetic retinopathy screening using two-field photography.
publisher Public Library of Science (PLoS)
publishDate 2011
url https://doaj.org/article/a249b448014a432a8b9449a60a98591a
work_keys_str_mv AT keithgoatman assessmentofautomateddiseasedetectionindiabeticretinopathyscreeningusingtwofieldphotography
AT amandacharnley assessmentofautomateddiseasedetectionindiabeticretinopathyscreeningusingtwofieldphotography
AT laurawebster assessmentofautomateddiseasedetectionindiabeticretinopathyscreeningusingtwofieldphotography
AT stephennussey assessmentofautomateddiseasedetectionindiabeticretinopathyscreeningusingtwofieldphotography
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