Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities

Abstract Long-term care facilities (LTCFs) bear disproportionate burden of COVID-19 and are prioritized for vaccine deployment. LTCF outbreaks could continue occurring during vaccine rollout due to incomplete population coverage, and the effect of vaccines on viral transmission are currently unknown...

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Autores principales:	Jay Love, Lindsay T. Keegan, Frederick J. Angulo, John M. McLaughlin, Kimberly M. Shea, David L. Swerdlow, Matthew H. Samore, Damon J. A. Toth
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a24a16603d7f4622b0b37fba0f0d1d0c
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spelling	oai:doaj.org-article:a24a16603d7f4622b0b37fba0f0d1d0c2021-12-02T17:41:13ZContinued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities10.1038/s41598-021-97612-w2045-2322https://doaj.org/article/a24a16603d7f4622b0b37fba0f0d1d0c2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-97612-whttps://doaj.org/toc/2045-2322Abstract Long-term care facilities (LTCFs) bear disproportionate burden of COVID-19 and are prioritized for vaccine deployment. LTCF outbreaks could continue occurring during vaccine rollout due to incomplete population coverage, and the effect of vaccines on viral transmission are currently unknown. Declining adherence to non-pharmaceutical interventions (NPIs) against within-facility transmission could therefore limit the effectiveness of vaccination. We built a stochastic model to simulate outbreaks in LTCF populations with differing vaccination coverage and NPI adherence to evaluate their interacting effects. Vaccination combined with strong NPI adherence produced the least morbidity and mortality. Healthcare worker vaccination improved outcomes in unvaccinated LTCF residents but was less impactful with declining NPI adherence. To prevent further illness and deaths, there is a continued need for NPIs in LTCFs during vaccine rollout.Jay LoveLindsay T. KeeganFrederick J. AnguloJohn M. McLaughlinKimberly M. SheaDavid L. SwerdlowMatthew H. SamoreDamon J. A. TothNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jay Love Lindsay T. Keegan Frederick J. Angulo John M. McLaughlin Kimberly M. Shea David L. Swerdlow Matthew H. Samore Damon J. A. Toth Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities
description	Abstract Long-term care facilities (LTCFs) bear disproportionate burden of COVID-19 and are prioritized for vaccine deployment. LTCF outbreaks could continue occurring during vaccine rollout due to incomplete population coverage, and the effect of vaccines on viral transmission are currently unknown. Declining adherence to non-pharmaceutical interventions (NPIs) against within-facility transmission could therefore limit the effectiveness of vaccination. We built a stochastic model to simulate outbreaks in LTCF populations with differing vaccination coverage and NPI adherence to evaluate their interacting effects. Vaccination combined with strong NPI adherence produced the least morbidity and mortality. Healthcare worker vaccination improved outcomes in unvaccinated LTCF residents but was less impactful with declining NPI adherence. To prevent further illness and deaths, there is a continued need for NPIs in LTCFs during vaccine rollout.
format	article
author	Jay Love Lindsay T. Keegan Frederick J. Angulo John M. McLaughlin Kimberly M. Shea David L. Swerdlow Matthew H. Samore Damon J. A. Toth
author_facet	Jay Love Lindsay T. Keegan Frederick J. Angulo John M. McLaughlin Kimberly M. Shea David L. Swerdlow Matthew H. Samore Damon J. A. Toth
author_sort	Jay Love
title	Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities
title_short	Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities
title_full	Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities
title_fullStr	Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities
title_full_unstemmed	Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities
title_sort	continued need for non-pharmaceutical interventions after covid-19 vaccination in long-term-care facilities
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a24a16603d7f4622b0b37fba0f0d1d0c
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Continued need for non-pharmaceutical interventions after COVID-19 vaccination in long-term-care facilities

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