Rational design of aptamer switches with programmable pH response
Previous design strategies for pH sensitive aptamers were not readily tunable across pH ranges. Here the authors present a general method to convert aptamers into pH-responsive switches using two orthogonal motifs.
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Auteurs principaux: | Ian A. P. Thompson, Liwei Zheng, Michael Eisenstein, H. Tom Soh |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Sujets: | |
Accès en ligne: | https://doaj.org/article/a24a2adf9c434bc799e6e407a56532c7 |
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