Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure

Extraorgan complications of acute destructive pancreatitis are registered in 60-95 % of patients. Liver failure is registered in one of the four patients with pancreatic necrosis. We analyzed the results of surgical treatment of 122 patients with acute destructive pancreatitis. We studied clinical i...

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Autores principales:	A. N. Plekhanov, D. I. Reshetnikov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	pancreatitis liver failure hemodynamics diagnostics Science Q
Acceso en línea:	https://doaj.org/article/a24e58d65666499682d5ccc725cd5833
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spelling	oai:doaj.org-article:a24e58d65666499682d5ccc725cd58332021-11-23T06:14:35ZPorto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure2541-94202587-959610.12737/22971https://doaj.org/article/a24e58d65666499682d5ccc725cd58332016-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/244https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Extraorgan complications of acute destructive pancreatitis are registered in 60-95 % of patients. Liver failure is registered in one of the four patients with pancreatic necrosis. We analyzed the results of surgical treatment of 122 patients with acute destructive pancreatitis. We studied clinical indicators of liver failure in 103 (84.4 %) patients with acute pancreatitis. The development of portal hypertension with decrease in hepatic volume perfusion is an important element in the pathogenesis of acute pancreatitis and associated liver function abnormalities. In patients with severe and moderate liver failure, the reduction of blood flow in portal vein was registered. It was caused by reduce of portal vein diameter and decrease in linear blood flow velocity. Destructive pancreatitis is accompanied by liver failure with hyperbilirubinemia, increased activity of cytolytic enzymes, incoordination in protein and carbohydrate metabolism as its common manifestations. An important factor in the pathogenesis of liver failure is a reduction of porto-hepatic hemodynamics and as a consequence - hepatic hypoperfusion.A. N. PlekhanovD. I. ReshetnikovScientific Сentre for Family Health and Human Reproduction Problemsarticlepancreatitisliver failurehemodynamicsdiagnosticsScienceQRUActa Biomedica Scientifica, Vol 1, Iss 4, Pp 68-71 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	pancreatitis liver failure hemodynamics diagnostics Science Q
spellingShingle	pancreatitis liver failure hemodynamics diagnostics Science Q A. N. Plekhanov D. I. Reshetnikov Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure
description	Extraorgan complications of acute destructive pancreatitis are registered in 60-95 % of patients. Liver failure is registered in one of the four patients with pancreatic necrosis. We analyzed the results of surgical treatment of 122 patients with acute destructive pancreatitis. We studied clinical indicators of liver failure in 103 (84.4 %) patients with acute pancreatitis. The development of portal hypertension with decrease in hepatic volume perfusion is an important element in the pathogenesis of acute pancreatitis and associated liver function abnormalities. In patients with severe and moderate liver failure, the reduction of blood flow in portal vein was registered. It was caused by reduce of portal vein diameter and decrease in linear blood flow velocity. Destructive pancreatitis is accompanied by liver failure with hyperbilirubinemia, increased activity of cytolytic enzymes, incoordination in protein and carbohydrate metabolism as its common manifestations. An important factor in the pathogenesis of liver failure is a reduction of porto-hepatic hemodynamics and as a consequence - hepatic hypoperfusion.
format	article
author	A. N. Plekhanov D. I. Reshetnikov
author_facet	A. N. Plekhanov D. I. Reshetnikov
author_sort	A. N. Plekhanov
title	Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure
title_short	Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure
title_full	Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure
title_fullStr	Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure
title_full_unstemmed	Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure
title_sort	porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/a24e58d65666499682d5ccc725cd5833
work_keys_str_mv	AT anplekhanov portohepatichemodynamicsinpatientswithdestructivepancreatitiscombinedwithliverfailure AT direshetnikov portohepatichemodynamicsinpatientswithdestructivepancreatitiscombinedwithliverfailure
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Porto-hepatic hemodynamics in patients with destructive pancreatitis combined with liver failure

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