The proteolipid protein promoter drives expression outside of the oligodendrocyte lineage during embryonic and early postnatal development.

The proteolipid protein (Plp) gene promoter is responsible for driving expression of one of the major components of myelin--PLP and its splice variant DM-20. Both products are classically thought to express predominantly in oligodendrocytes. However, accumulating evidence suggests Plp expression is...

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Autores principales: John-Paul Michalski, Carrie Anderson, Ariane Beauvais, Yves De Repentigny, Rashmi Kothary
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/a251cac494a0407286b85f52f2fcb1ac
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