Variant antigen diversity in Trypanosoma vivax is not driven by recombination

Variant antigen diversity in Trypanosoma vivax is not driven by recombination

Trypanosoma rely on variant surface glycoprotein (VSG) to escape host immunity, but mechanisms generating antigenic diversity of VSG are poorly understood. Here, Silva-Pereira et al. show that T. vivax has a limited antigenic repertoire compared to T. brucei and that recombination plays little role...

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Bibliographic Details
Main Authors: Sara Silva Pereira, Kayo J. G. de Almeida Castilho Neto, Craig W. Duffy, Peter Richards, Harry Noyes, Moses Ogugo, Marcos Rogério André, Zakaria Bengaly, Steve Kemp, Marta M. G. Teixeira, Rosangela Z. Machado, Andrew P. Jackson
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/a256b8b60abb41049cc82d1a6b1db3ac
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