Prediction of anti-CD25 and 5-FU treatments efficacy for pancreatic cancer using a mathematical model

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with rising incidence and with 5-years overall survival of less than 8%. PDAC creates an immune-suppressive tumor microenvironment to escape immune-mediated eradication. Regulatory T (Treg) cells and myeloid-deriv...

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Autores principales: Sajad Shafiekhani, Hojat Dehghanbanadaki, Azam Sadat Fatemi, Sara Rahbar, Jamshid Hadjati, Amir Homayoun Jafari
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/a2604ce40f084ba89a35729eb57b16c3
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