Telomeric RNAs are essential to maintain telomeres

The telomeric long-non coding RNA, TERRA, has been proposed in the past to modulate different telomeric functions based on in vitrostudies. Here the authors show, using a genetic deletion approach, that TERRA is transcribed from the 20q subtelomere and that it is essential for telomere maintenance.

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Autores principales:	Juan José Montero, Isabel López de Silanes, Osvaldo Graña, Maria A. Blasco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a26156584d304f77b725f7293e0954ab
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spelling	oai:doaj.org-article:a26156584d304f77b725f7293e0954ab2021-12-02T15:35:25ZTelomeric RNAs are essential to maintain telomeres10.1038/ncomms125342041-1723https://doaj.org/article/a26156584d304f77b725f7293e0954ab2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12534https://doaj.org/toc/2041-1723The telomeric long-non coding RNA, TERRA, has been proposed in the past to modulate different telomeric functions based on in vitrostudies. Here the authors show, using a genetic deletion approach, that TERRA is transcribed from the 20q subtelomere and that it is essential for telomere maintenance.Juan José MonteroIsabel López de SilanesOsvaldo GrañaMaria A. BlascoNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Juan José Montero Isabel López de Silanes Osvaldo Graña Maria A. Blasco Telomeric RNAs are essential to maintain telomeres
description	The telomeric long-non coding RNA, TERRA, has been proposed in the past to modulate different telomeric functions based on in vitrostudies. Here the authors show, using a genetic deletion approach, that TERRA is transcribed from the 20q subtelomere and that it is essential for telomere maintenance.
format	article
author	Juan José Montero Isabel López de Silanes Osvaldo Graña Maria A. Blasco
author_facet	Juan José Montero Isabel López de Silanes Osvaldo Graña Maria A. Blasco
author_sort	Juan José Montero
title	Telomeric RNAs are essential to maintain telomeres
title_short	Telomeric RNAs are essential to maintain telomeres
title_full	Telomeric RNAs are essential to maintain telomeres
title_fullStr	Telomeric RNAs are essential to maintain telomeres
title_full_unstemmed	Telomeric RNAs are essential to maintain telomeres
title_sort	telomeric rnas are essential to maintain telomeres
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/a26156584d304f77b725f7293e0954ab
work_keys_str_mv	AT juanjosemontero telomericrnasareessentialtomaintaintelomeres AT isabellopezdesilanes telomericrnasareessentialtomaintaintelomeres AT osvaldograna telomericrnasareessentialtomaintaintelomeres AT mariaablasco telomericrnasareessentialtomaintaintelomeres
_version_	1718386551626399744

Telomeric RNAs are essential to maintain telomeres

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