Telomeric RNAs are essential to maintain telomeres
The telomeric long-non coding RNA, TERRA, has been proposed in the past to modulate different telomeric functions based on in vitrostudies. Here the authors show, using a genetic deletion approach, that TERRA is transcribed from the 20q subtelomere and that it is essential for telomere maintenance.
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Autores principales: | Juan José Montero, Isabel López de Silanes, Osvaldo Graña, Maria A. Blasco |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/a26156584d304f77b725f7293e0954ab |
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