Telomeric RNAs are essential to maintain telomeres

The telomeric long-non coding RNA, TERRA, has been proposed in the past to modulate different telomeric functions based on in vitrostudies. Here the authors show, using a genetic deletion approach, that TERRA is transcribed from the 20q subtelomere and that it is essential for telomere maintenance.

Saved in:
Bibliographic Details
Main Authors: Juan José Montero, Isabel López de Silanes, Osvaldo Graña, Maria A. Blasco
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/a26156584d304f77b725f7293e0954ab
Tags: Add Tag
No Tags, Be the first to tag this record!