Telomeric RNAs are essential to maintain telomeres

The telomeric long-non coding RNA, TERRA, has been proposed in the past to modulate different telomeric functions based on in vitrostudies. Here the authors show, using a genetic deletion approach, that TERRA is transcribed from the 20q subtelomere and that it is essential for telomere maintenance.

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Auteurs principaux: Juan José Montero, Isabel López de Silanes, Osvaldo Graña, Maria A. Blasco
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Q
Accès en ligne:https://doaj.org/article/a26156584d304f77b725f7293e0954ab
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