FBW7 couples structural integrity with functional output of primary cilia

FBW7 couples structural integrity with functional output of primary cilia

Petsouki et al. dissect the importance of FBW7-mediated regulation of NDE1 and TALPID3 in mesenchymal stem cells (MSCs). They find that by modulating the abundance of negative (NDE1) and positive (TALPID3) cilia regulators, FBW7 contributes to both the assembly and signaling functions of primary cil...

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Autores principales: Eleni Petsouki, Vasileios Gerakopoulos, Nicholas Szeto, Wenhan Chang, Mary Beth Humphrey, Leonidas Tsiokas
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/a269982ff2f24864a1170fac0d97006f
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