Highly Basic Clusters in the Herpes Simplex Virus 1 Nuclear Egress Complex Drive Membrane Budding by Inducing Lipid Ordering
ABSTRACT During replication of herpesviruses, capsids escape from the nucleus into the cytoplasm by budding at the inner nuclear membrane. This unusual process is mediated by the viral nuclear egress complex (NEC) that deforms the membrane around the capsid by oligomerizing into a hexagonal, membran...
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| Auteurs principaux: | Michael K. Thorsen, Alex Lai, Michelle W. Lee, David P. Hoogerheide, Gerard C. L. Wong, Jack H. Freed, Ekaterina E. Heldwein |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/a2728f92d10644fab661b50a6946efa7 |
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