miQC: An adaptive probabilistic framework for quality control of single-cell RNA-sequencing data.

Single-cell RNA-sequencing (scRNA-seq) has made it possible to profile gene expression in tissues at high resolution. An important preprocessing step prior to performing downstream analyses is to identify and remove cells with poor or degraded sample quality using quality control (QC) metrics. Two w...

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Auteurs principaux: Ariel A Hippen, Matias M Falco, Lukas M Weber, Erdogan Pekcan Erkan, Kaiyang Zhang, Jennifer Anne Doherty, Anna Vähärautio, Casey S Greene, Stephanie C Hicks
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/a27474f972ea4229a2ac4f764625b728
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