Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN |
| Published: |
KeAi Communications Co., Ltd.
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/a278f990158342e99091a9ef1ecb8fee |
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| Summary: | Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs) were stable and evaluated by SEM, HR-TEM, UV–vis and FT-IR spectroscopy and they were spherical in shape, homogenous with an average diameter of 20 nm along with long term stability. The CUR-AuNPs were tested for their antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Escherichia coli and displayed significant antibacterial activity. CUR-AuNPs showed maximum inhibition efficiency of 94% by the human red blood cell method. CUR-AuNPs also exhibited significant antioxidant and radical scavenging activities. This study sets a platform for novel synthetic AuNPs formed by utilizing reducing agents in form of isolated curcumin to effectively exploit the biomedical application of the particles. |
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