Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities

Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs...

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Autores principales: N. Muniyappan, M. Pandeeswaran, Augustine Amalraj
Formato: article
Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2021
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Acceso en línea:https://doaj.org/article/a278f990158342e99091a9ef1ecb8fee
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spelling oai:doaj.org-article:a278f990158342e99091a9ef1ecb8fee2021-11-16T04:11:11ZGreen synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities2590-182610.1016/j.enceco.2021.01.002https://doaj.org/article/a278f990158342e99091a9ef1ecb8fee2021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2590182621000035https://doaj.org/toc/2590-1826Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs) were stable and evaluated by SEM, HR-TEM, UV–vis and FT-IR spectroscopy and they were spherical in shape, homogenous with an average diameter of 20 nm along with long term stability. The CUR-AuNPs were tested for their antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Escherichia coli and displayed significant antibacterial activity. CUR-AuNPs showed maximum inhibition efficiency of 94% by the human red blood cell method. CUR-AuNPs also exhibited significant antioxidant and radical scavenging activities. This study sets a platform for novel synthetic AuNPs formed by utilizing reducing agents in form of isolated curcumin to effectively exploit the biomedical application of the particles.N. MuniyappanM. PandeeswaranAugustine AmalrajKeAi Communications Co., Ltd.articleCurcuma pseudomontana rhizomeHill turmericCurcuminGold nanoparticlesBiological activitiesEnvironmental technology. Sanitary engineeringTD1-1066ENEnvironmental Chemistry and Ecotoxicology, Vol 3, Iss , Pp 117-124 (2021)
institution DOAJ
collection DOAJ
language EN
topic Curcuma pseudomontana rhizome
Hill turmeric
Curcumin
Gold nanoparticles
Biological activities
Environmental technology. Sanitary engineering
TD1-1066
spellingShingle Curcuma pseudomontana rhizome
Hill turmeric
Curcumin
Gold nanoparticles
Biological activities
Environmental technology. Sanitary engineering
TD1-1066
N. Muniyappan
M. Pandeeswaran
Augustine Amalraj
Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
description Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs) were stable and evaluated by SEM, HR-TEM, UV–vis and FT-IR spectroscopy and they were spherical in shape, homogenous with an average diameter of 20 nm along with long term stability. The CUR-AuNPs were tested for their antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Escherichia coli and displayed significant antibacterial activity. CUR-AuNPs showed maximum inhibition efficiency of 94% by the human red blood cell method. CUR-AuNPs also exhibited significant antioxidant and radical scavenging activities. This study sets a platform for novel synthetic AuNPs formed by utilizing reducing agents in form of isolated curcumin to effectively exploit the biomedical application of the particles.
format article
author N. Muniyappan
M. Pandeeswaran
Augustine Amalraj
author_facet N. Muniyappan
M. Pandeeswaran
Augustine Amalraj
author_sort N. Muniyappan
title Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
title_short Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
title_full Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
title_fullStr Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
title_full_unstemmed Green synthesis of gold nanoparticles using Curcuma pseudomontana isolated curcumin: Its characterization, antimicrobial, antioxidant and anti- inflammatory activities
title_sort green synthesis of gold nanoparticles using curcuma pseudomontana isolated curcumin: its characterization, antimicrobial, antioxidant and anti- inflammatory activities
publisher KeAi Communications Co., Ltd.
publishDate 2021
url https://doaj.org/article/a278f990158342e99091a9ef1ecb8fee
work_keys_str_mv AT nmuniyappan greensynthesisofgoldnanoparticlesusingcurcumapseudomontanaisolatedcurcuminitscharacterizationantimicrobialantioxidantandantiinflammatoryactivities
AT mpandeeswaran greensynthesisofgoldnanoparticlesusingcurcumapseudomontanaisolatedcurcuminitscharacterizationantimicrobialantioxidantandantiinflammatoryactivities
AT augustineamalraj greensynthesisofgoldnanoparticlesusingcurcumapseudomontanaisolatedcurcuminitscharacterizationantimicrobialantioxidantandantiinflammatoryactivities
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