Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma

Abstract Purpose: Viscocanalostomy represents an alternative to standard penetrating glaucoma surgery. The aim of this study is to compare the outcomes of combined phacoemulsification and viscocanalostomy in eyes with primary open-angle glaucoma (POAG) versus eyes with pseudoexfoliation glaucoma (PE...

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Autores principales: Ebrahim Azaripour, Yaser Khakpour, Reza Soltani-Moghadam, Zahra Moravvej, Abdolreza Medghalchi, Hassan Behboudi, Yousef Alizadeh, Soheil Soltanipour, Shila Kianmehr
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Publicado: Knowledge E 2021
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spelling oai:doaj.org-article:a27c0db7fbd24119990703a5973c99a02021-11-09T08:05:35ZOutcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma2008-20102008-322X10.18502/jovr.v16i4.9746https://doaj.org/article/a27c0db7fbd24119990703a5973c99a02021-10-01T00:00:00Zhttps://doi.org/10.18502/jovr.v16i4.9746https://doaj.org/toc/2008-2010https://doaj.org/toc/2008-322XAbstract Purpose: Viscocanalostomy represents an alternative to standard penetrating glaucoma surgery. The aim of this study is to compare the outcomes of combined phacoemulsification and viscocanalostomy in eyes with primary open-angle glaucoma (POAG) versus eyes with pseudoexfoliation glaucoma (PEXG). Methods: In this prospective non-randomized comparative study, eyes with cataract and POAG or PEXG were enrolled. Pre- and postoperative data including best corrected visual acuity (BCVA), intraocular pressure (IOP), and the number of antiglaucoma medications administered were recorded at each visit. All patients underwent phacoviscocanalostomy. Complete success was defined as the IOP of 21 mmHg or less without the administration of medication while a qualified success reported the same IOP parameters either with or without the administration of medication. Results: Fifty-four eyes with POAG and fifty-four with PEXG underwent phacoviscocanalostomy. The mean follow-up time was 23.36 ± 8.8 months (range, 6–40 months). The mean postoperative IOP reduced significantly in both groups, although the mean IOP reduction was significantly greater in PEXG eyes (14.7 ± 8.9 vs 10.1 ± 7.7 mmHg) (P = 0.05). At the final follow-up visit, the mean postoperative IOP was 14.1 ± 2.1 and 16.6 ± 3.5 mmHg in the PEXG and POAG eyes, respectively (P = 0.001). A complete success rate of 88.9% and 75.9% was achieved in PEXG and POAG eyes, respectively (P = 0.07). The qualified success rate was 100% in the PEXG and 85.2% in POAG groups (P = 0.03). Conclusion: Phacoviscocanalostomy achieved significant IOP reduction and visual improvement in both POAG and PEXG patients. Our results indicated that in terms of IOP reduction, this procedure was more effective in treating PEXG.Ebrahim AzaripourYaser KhakpourReza Soltani-MoghadamZahra MoravvejAbdolreza MedghalchiHassan BehboudiYousef AlizadehSoheil SoltanipourShila KianmehrKnowledge Earticleprimary open-angle glaucoma intraocular pressurephacoviscocanalostomypseudoexfoliationOphthalmologyRE1-994ENJournal of Ophthalmic & Vision Research, Vol 16, Iss 4, Pp 566-573 (2021)
institution DOAJ
collection DOAJ
language EN
topic primary open-angle glaucoma intraocular pressure
phacoviscocanalostomy
pseudoexfoliation
Ophthalmology
RE1-994
spellingShingle primary open-angle glaucoma intraocular pressure
phacoviscocanalostomy
pseudoexfoliation
Ophthalmology
RE1-994
Ebrahim Azaripour
Yaser Khakpour
Reza Soltani-Moghadam
Zahra Moravvej
Abdolreza Medghalchi
Hassan Behboudi
Yousef Alizadeh
Soheil Soltanipour
Shila Kianmehr
Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma
description Abstract Purpose: Viscocanalostomy represents an alternative to standard penetrating glaucoma surgery. The aim of this study is to compare the outcomes of combined phacoemulsification and viscocanalostomy in eyes with primary open-angle glaucoma (POAG) versus eyes with pseudoexfoliation glaucoma (PEXG). Methods: In this prospective non-randomized comparative study, eyes with cataract and POAG or PEXG were enrolled. Pre- and postoperative data including best corrected visual acuity (BCVA), intraocular pressure (IOP), and the number of antiglaucoma medications administered were recorded at each visit. All patients underwent phacoviscocanalostomy. Complete success was defined as the IOP of 21 mmHg or less without the administration of medication while a qualified success reported the same IOP parameters either with or without the administration of medication. Results: Fifty-four eyes with POAG and fifty-four with PEXG underwent phacoviscocanalostomy. The mean follow-up time was 23.36 ± 8.8 months (range, 6–40 months). The mean postoperative IOP reduced significantly in both groups, although the mean IOP reduction was significantly greater in PEXG eyes (14.7 ± 8.9 vs 10.1 ± 7.7 mmHg) (P = 0.05). At the final follow-up visit, the mean postoperative IOP was 14.1 ± 2.1 and 16.6 ± 3.5 mmHg in the PEXG and POAG eyes, respectively (P = 0.001). A complete success rate of 88.9% and 75.9% was achieved in PEXG and POAG eyes, respectively (P = 0.07). The qualified success rate was 100% in the PEXG and 85.2% in POAG groups (P = 0.03). Conclusion: Phacoviscocanalostomy achieved significant IOP reduction and visual improvement in both POAG and PEXG patients. Our results indicated that in terms of IOP reduction, this procedure was more effective in treating PEXG.
format article
author Ebrahim Azaripour
Yaser Khakpour
Reza Soltani-Moghadam
Zahra Moravvej
Abdolreza Medghalchi
Hassan Behboudi
Yousef Alizadeh
Soheil Soltanipour
Shila Kianmehr
author_facet Ebrahim Azaripour
Yaser Khakpour
Reza Soltani-Moghadam
Zahra Moravvej
Abdolreza Medghalchi
Hassan Behboudi
Yousef Alizadeh
Soheil Soltanipour
Shila Kianmehr
author_sort Ebrahim Azaripour
title Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma
title_short Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma
title_full Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma
title_fullStr Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma
title_full_unstemmed Outcomes of Phaco-viscocanalostomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma
title_sort outcomes of phaco-viscocanalostomy in primary open angle glaucoma versus pseudoexfoliation glaucoma
publisher Knowledge E
publishDate 2021
url https://doaj.org/article/a27c0db7fbd24119990703a5973c99a0
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