Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34

Resistance of Neisseria gonorrhoeae to extended spectrum cephalosporins is an increasing concern. Here, the authors conduct whole genome sequencing of isolates from the United States and find that most resistant isolates were associated with a persistent circulating lineage.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jesse C. Thomas, Sandeep J. Joseph, John C. Cartee, Cau D. Pham, Matthew W. Schmerer, Karen Schlanger, Sancta B. St. Cyr, Ellen N. Kersh, Brian H. Raphael, the Antimicrobial Resistant Neisseria gonorrhoeae Working Group
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a2803c0716a344b2a66b94088469d60a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a2803c0716a344b2a66b94088469d60a
record_format	dspace
spelling	oai:doaj.org-article:a2803c0716a344b2a66b94088469d60a2021-12-02T18:02:46ZPhylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-3410.1038/s41467-021-24072-12041-1723https://doaj.org/article/a2803c0716a344b2a66b94088469d60a2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24072-1https://doaj.org/toc/2041-1723Resistance of Neisseria gonorrhoeae to extended spectrum cephalosporins is an increasing concern. Here, the authors conduct whole genome sequencing of isolates from the United States and find that most resistant isolates were associated with a persistent circulating lineage.Jesse C. ThomasSandeep J. JosephJohn C. CarteeCau D. PhamMatthew W. SchmererKaren SchlangerSancta B. St. CyrEllen N. KershBrian H. Raphaelthe Antimicrobial Resistant Neisseria gonorrhoeae Working GroupNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jesse C. Thomas Sandeep J. Joseph John C. Cartee Cau D. Pham Matthew W. Schmerer Karen Schlanger Sancta B. St. Cyr Ellen N. Kersh Brian H. Raphael the Antimicrobial Resistant Neisseria gonorrhoeae Working Group Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34
description	Resistance of Neisseria gonorrhoeae to extended spectrum cephalosporins is an increasing concern. Here, the authors conduct whole genome sequencing of isolates from the United States and find that most resistant isolates were associated with a persistent circulating lineage.
format	article
author	Jesse C. Thomas Sandeep J. Joseph John C. Cartee Cau D. Pham Matthew W. Schmerer Karen Schlanger Sancta B. St. Cyr Ellen N. Kersh Brian H. Raphael the Antimicrobial Resistant Neisseria gonorrhoeae Working Group
author_facet	Jesse C. Thomas Sandeep J. Joseph John C. Cartee Cau D. Pham Matthew W. Schmerer Karen Schlanger Sancta B. St. Cyr Ellen N. Kersh Brian H. Raphael the Antimicrobial Resistant Neisseria gonorrhoeae Working Group
author_sort	Jesse C. Thomas
title	Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34
title_short	Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34
title_full	Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34
title_fullStr	Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34
title_full_unstemmed	Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34
title_sort	phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic pena-34
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a2803c0716a344b2a66b94088469d60a
work_keys_str_mv	AT jessecthomas phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT sandeepjjoseph phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT johnccartee phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT caudpham phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT matthewwschmerer phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT karenschlanger phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT sanctabstcyr phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT ellennkersh phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT brianhraphael phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34 AT theantimicrobialresistantneisseriagonorrhoeaeworkinggroup phylogenomicanalysisrevealspersistenceofgonococcalstrainswithreducedsusceptibilitytoextendedspectrumcephalosporinsandmosaicpena34
_version_	1718378886297812992

Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34

Ejemplares similares