The Role of the Ocular Tissue in SARS-CoV-2 Transmission

Michael Peng,1 Jiannong Dai,1 Chenna Kesavulu Sugali,1 Naga Pradeep Rayana,1 Weiming Mao1,2 1Department of Ophthalmology, Eugene & Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN, USA; 2Department of Biochemistry and Molecular Biology, Indiana University...

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Autores principales:	Peng M, Dai J, Sugali CK, Rayana NP, Mao W
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	covid-19 sars-cov-2 eye transmission ace2 Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/a286b46c990c471faf0b961dece84379
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spelling	oai:doaj.org-article:a286b46c990c471faf0b961dece843792021-12-02T11:59:46ZThe Role of the Ocular Tissue in SARS-CoV-2 Transmission1177-5483https://doaj.org/article/a286b46c990c471faf0b961dece843792020-10-01T00:00:00Zhttps://www.dovepress.com/the-role-of-the-ocular-tissue-in-sars-cov-2-transmission-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Michael Peng,1 Jiannong Dai,1 Chenna Kesavulu Sugali,1 Naga Pradeep Rayana,1 Weiming Mao1,2 1Department of Ophthalmology, Eugene & Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN, USA; 2Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USACorrespondence: Weiming MaoDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USATel +1 317-278-0801Email weimmao@iu.eduAbstract: The current global pandemic of coronavirus disease 2019 (COVID-19) has affected over 21 million people and caused over half a million deaths within a few months. COVID-19 has become one of the most severe public health crises in recent years. Compared to other pathogenic coronaviruses, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly infectious. Due to the lack of specific and effective treatment or vaccines, disease prevention and early detection are essential for establishing guidelines to mitigate further spread. The potential role of the ocular system in COVID-19 is still not clear but it has gained increasing attention. Here, we reviewed both clinical and research evidence on the ocular manifestations associated with COVID-19, the presence of SARS-CoV-2 in ocular surface tissues and tears, and the potential role of the eye in contracting SARS-CoV-2.Keywords: COVID-19, SARS-CoV-2, eye, transmission, ACE2Peng MDai JSugali CKRayana NPMao WDove Medical Pressarticlecovid-19sars-cov-2eyetransmissionace2OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 3017-3024 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 sars-cov-2 eye transmission ace2 Ophthalmology RE1-994
spellingShingle	covid-19 sars-cov-2 eye transmission ace2 Ophthalmology RE1-994 Peng M Dai J Sugali CK Rayana NP Mao W The Role of the Ocular Tissue in SARS-CoV-2 Transmission
description	Michael Peng,1 Jiannong Dai,1 Chenna Kesavulu Sugali,1 Naga Pradeep Rayana,1 Weiming Mao1,2 1Department of Ophthalmology, Eugene & Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN, USA; 2Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USACorrespondence: Weiming MaoDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USATel +1 317-278-0801Email weimmao@iu.eduAbstract: The current global pandemic of coronavirus disease 2019 (COVID-19) has affected over 21 million people and caused over half a million deaths within a few months. COVID-19 has become one of the most severe public health crises in recent years. Compared to other pathogenic coronaviruses, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly infectious. Due to the lack of specific and effective treatment or vaccines, disease prevention and early detection are essential for establishing guidelines to mitigate further spread. The potential role of the ocular system in COVID-19 is still not clear but it has gained increasing attention. Here, we reviewed both clinical and research evidence on the ocular manifestations associated with COVID-19, the presence of SARS-CoV-2 in ocular surface tissues and tears, and the potential role of the eye in contracting SARS-CoV-2.Keywords: COVID-19, SARS-CoV-2, eye, transmission, ACE2
format	article
author	Peng M Dai J Sugali CK Rayana NP Mao W
author_facet	Peng M Dai J Sugali CK Rayana NP Mao W
author_sort	Peng M
title	The Role of the Ocular Tissue in SARS-CoV-2 Transmission
title_short	The Role of the Ocular Tissue in SARS-CoV-2 Transmission
title_full	The Role of the Ocular Tissue in SARS-CoV-2 Transmission
title_fullStr	The Role of the Ocular Tissue in SARS-CoV-2 Transmission
title_full_unstemmed	The Role of the Ocular Tissue in SARS-CoV-2 Transmission
title_sort	role of the ocular tissue in sars-cov-2 transmission
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/a286b46c990c471faf0b961dece84379
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The Role of the Ocular Tissue in SARS-CoV-2 Transmission

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