Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCCSummary

Background & Aims: Activation of the kelch-like ECH-associated protein 1 (Keap1)–nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway has been associated with metabolic reprogramming in many tumors, including hepatocellular carcinoma (HCC). However, the contribution of Nrf2 mutations i...

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Autores principales:	Sandra Mattu, Patrizia Zavattari, Marta Anna Kowalik, Marina Serra, Pia Sulas, Rajesh Pal, Elisabetta Puliga, Salvatore Sutti, Beatrice Foglia, Maurizio Parola, Emanuele Albano, Silvia Giordano, Andrea Perra, Amedeo Columbano
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Nrf2 Ctnnb1 Gene Mutation Metabolic Reprogramming HCC Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/a287ac6f649144fb9e8b07c7fac86783
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Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCCSummary

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