Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children

Enterovirus 71 is a leading cause of hand-foot-and-mouth disease and herpangina. Here, the authors characterize a large panel of plasmablast-derived IgG mAbs that target the capsid of EV71 to identify neutralizing antibodies induced by natural infection.

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Autores principales:	Kuan-Ying Arthur Huang, Mei-Feng Chen, Yhu-Chering Huang, Shin-Ru Shih, Cheng-Hsun Chiu, Jainn-Jim Lin, Jen-Ren Wang, Kuo-Chien Tsao, Tzou-Yien Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a293485c5d194c97bf8cca5e0af275ba
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spelling	oai:doaj.org-article:a293485c5d194c97bf8cca5e0af275ba2021-12-02T15:38:49ZEpitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children10.1038/s41467-017-00736-92041-1723https://doaj.org/article/a293485c5d194c97bf8cca5e0af275ba2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00736-9https://doaj.org/toc/2041-1723Enterovirus 71 is a leading cause of hand-foot-and-mouth disease and herpangina. Here, the authors characterize a large panel of plasmablast-derived IgG mAbs that target the capsid of EV71 to identify neutralizing antibodies induced by natural infection.Kuan-Ying Arthur HuangMei-Feng ChenYhu-Chering HuangShin-Ru ShihCheng-Hsun ChiuJainn-Jim LinJen-Ren WangKuo-Chien TsaoTzou-Yien LinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kuan-Ying Arthur Huang Mei-Feng Chen Yhu-Chering Huang Shin-Ru Shih Cheng-Hsun Chiu Jainn-Jim Lin Jen-Ren Wang Kuo-Chien Tsao Tzou-Yien Lin Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children
description	Enterovirus 71 is a leading cause of hand-foot-and-mouth disease and herpangina. Here, the authors characterize a large panel of plasmablast-derived IgG mAbs that target the capsid of EV71 to identify neutralizing antibodies induced by natural infection.
format	article
author	Kuan-Ying Arthur Huang Mei-Feng Chen Yhu-Chering Huang Shin-Ru Shih Cheng-Hsun Chiu Jainn-Jim Lin Jen-Ren Wang Kuo-Chien Tsao Tzou-Yien Lin
author_facet	Kuan-Ying Arthur Huang Mei-Feng Chen Yhu-Chering Huang Shin-Ru Shih Cheng-Hsun Chiu Jainn-Jim Lin Jen-Ren Wang Kuo-Chien Tsao Tzou-Yien Lin
author_sort	Kuan-Ying Arthur Huang
title	Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children
title_short	Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children
title_full	Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children
title_fullStr	Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children
title_full_unstemmed	Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children
title_sort	epitope-associated and specificity-focused features of ev71-neutralizing antibody repertoires from plasmablasts of infected children
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a293485c5d194c97bf8cca5e0af275ba
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Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children

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